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delta-sultam

 
National Institutes of Health

Papers overview

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2017
2017
We report the diastereoselective synthesis of novel spiropiperidine templates for use in SAR studies of β-secretase (BACE… Expand
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2009
2009
Many sultam derivatives were found to possess valuable therapeutic properties such as antitumor activity[1] and anticonvulsive… Expand
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2006
2006
Novel sultam hydroxamates with potent MMP activity were transformed into potent TACE inhibitors, lacking MMP activity. To… Expand
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2006
2006
[reaction: see text] An efficient protocol has been developed using D-(2R)-Oppolzer sultam as a chiral auxiliary for generating… Expand
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2004
2004
In this communication we describe the design, synthesis, and evaluation of novel sultam hydroxamates 4 as MMP-2, -9, and -13… Expand
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