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dehydroapratoxin A

Known as: dehydro-apratoxin A 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Depsipeptides

Narrower (1)

E-dehydroapratoxin A

Papers overview

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Highly Cited
2016
Highly Cited
2016
Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel.
Highly Cited
2013
Highly Cited
2013
Apratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.
Cultivation of the marine cyanobacterium Moorea producens, collected from the Nabq Mangroves in the Gulf of Aqaba (Red Sea), led… 
Highly Cited
2011
Highly Cited
2011
Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity
Apratoxins are cytotoxic marine natural products that prevent cotranslational translocation early in the secretory pathway. We… 
Highly Cited
2009
Highly Cited
2009
Apratoxin A Reversibly Inhibits the Secretory Pathway by Preventing Cotranslational Translocation
Apratoxin A is a potent cytotoxic marine natural product that rapidly inhibits signal transducer and activator of transcription… 
Highly Cited
2009
Highly Cited
2009
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy
Promoting the degradation of Hsp90 client proteins by inhibiting Hsp90, an important protein chaperone, has been shown to be a… 
2009
2009
Total synthesis of (-)-apratoxin A, 34-epimer, and its oxazoline analogue.
A concise and convergent total synthesis of the highly cytotoxic marine natural product apratoxin A is accomplished by an 18-step… 
Highly Cited
2008
Highly Cited
2008
Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida.
Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya… 
Highly Cited
2008
Highly Cited
2008
Apratoxin E, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium Lyngbya bouillonii.
A collection of the marine cyanobacterium Lyngbya bouillonii from Guam afforded apratoxin E (1), a new peptide-polyketide hybrid… 
Highly Cited
2006
Highly Cited
2006
A functional genomics approach to the mode of action of apratoxin A
The cyanobacterial metabolite apratoxin A (1) demonstrates potent cytotoxicity against tumor cell lines by a hitherto unknown… 
Highly Cited
2004
Highly Cited
2004
Total synthesis of the marine cyanobacterial cyclodepsipeptide apratoxin A.
A total synthesis of apratoxin A was developed. Apratoxin A, isolated from Lyngbya spp. cyanobacteria, is representative of a… 
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