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dehydroapratoxin A

Known as: dehydro-apratoxin A 
 
National Institutes of Health

Papers overview

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2016
2016
Apratoxin A is a cytotoxic natural product that prevents the biogenesis of secretory and membrane proteins. Biochemically… Expand
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2013
2013
Cultivation of the marine cyanobacterium Moorea producens, collected from the Nabq Mangroves in the Gulf of Aqaba (Red Sea), led… Expand
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2013
2013
The tropical marine cyanobacterium, Moorea bouillonii, has gained recent attention as a rich source of bioactive natural products… Expand
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2012
2012
The first asymmetric total synthesis of the marine natural product apratoxin D, a highly potent inhibitor of H-460 human lung… Expand
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2011
2011
Apratoxins are cytotoxic marine natural products that prevent cotranslational translocation early in the secretory pathway. We… Expand
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Highly Cited
2009
Highly Cited
2009
Apratoxin A is a potent cytotoxic marine natural product that rapidly inhibits signal transducer and activator of transcription… Expand
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2009
2009
Promoting the degradation of Hsp90 client proteins by inhibiting Hsp90, an important protein chaperone, has been shown to be a… Expand
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Highly Cited
2008
Highly Cited
2008
Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya… Expand
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Highly Cited
2006
Highly Cited
2006
The cyanobacterial metabolite apratoxin A (1) demonstrates potent cytotoxicity against tumor cell lines by a hitherto unknown… Expand
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2006
2006
A novel total synthesis of apratoxin A is described, with key steps including the assembly of its ketide segment through a D… Expand
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