Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

dehydroapratoxin A

Known as: dehydro-apratoxin A 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Apratoxin A is a cytotoxic natural product that prevents the biogenesis of secretory and membrane proteins. Biochemically… Expand
Highly Cited
2013
Highly Cited
2013
Cultivation of the marine cyanobacterium Moorea producens, collected from the Nabq Mangroves in the Gulf of Aqaba (Red Sea), led… Expand
Highly Cited
2011
Highly Cited
2011
Apratoxins are cytotoxic marine natural products that prevent cotranslational translocation early in the secretory pathway. We… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2009
Highly Cited
2009
Apratoxin A is a potent cytotoxic marine natural product that rapidly inhibits signal transducer and activator of transcription… Expand
  • table 1
Highly Cited
2009
Highly Cited
2009
Promoting the degradation of Hsp90 client proteins by inhibiting Hsp90, an important protein chaperone, has been shown to be a… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2008
Highly Cited
2008
Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya… Expand
Highly Cited
2008
Highly Cited
2008
A collection of the marine cyanobacterium Lyngbya bouillonii from Guam afforded apratoxin E (1), a new peptide-polyketide hybrid… Expand
Highly Cited
2006
Highly Cited
2006
The cyanobacterial metabolite apratoxin A (1) demonstrates potent cytotoxicity against tumor cell lines by a hitherto unknown… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Highly Cited
2006
Highly Cited
2006
A novel total synthesis of apratoxin A is described, with key steps including the assembly of its ketide segment through a D… Expand
Highly Cited
2006
Highly Cited
2006
[reaction: see text]. We have achieved a total synthesis of apratoxin A in which thiazoline formation was accomplished from the… Expand