Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,212,284 papers from all fields of science
Search
Sign In
Create Free Account
dehydroapratoxin A
Known as:
dehydro-apratoxin A
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Broader (1)
Depsipeptides
Narrower (1)
E-dehydroapratoxin A
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel.
A. Paatero
,
J. Kellosalo
,
+5 authors
V. Paavilainen
Cell Chemical Biology
2016
Corpus ID: 44770392
Highly Cited
2013
Highly Cited
2013
Apratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.
C. Thornburg
,
E. Cowley
,
+4 authors
K. McPhail
Journal of Natural Products
2013
Corpus ID: 42734149
Cultivation of the marine cyanobacterium Moorea producens, collected from the Nabq Mangroves in the Gulf of Aqaba (Red Sea), led…
Expand
Highly Cited
2011
Highly Cited
2011
Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity
Qi-Yin Chen
,
Yanxia Liu
,
H. Luesch
ACS Medicinal Chemistry Letters
2011
Corpus ID: 14136690
Apratoxins are cytotoxic marine natural products that prevent cotranslational translocation early in the secretory pathway. We…
Expand
Highly Cited
2009
Highly Cited
2009
Apratoxin A Reversibly Inhibits the Secretory Pathway by Preventing Cotranslational Translocation
Yanxia Liu
,
B. Law
,
H. Luesch
Molecular Pharmacology
2009
Corpus ID: 6698633
Apratoxin A is a potent cytotoxic marine natural product that rapidly inhibits signal transducer and activator of transcription…
Expand
Highly Cited
2009
Highly Cited
2009
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy
S. Shen
,
Pengtao Zhang
,
+7 authors
Qiang Yu
Journal of Cell Biology
2009
Corpus ID: 232454
Promoting the degradation of Hsp90 client proteins by inhibiting Hsp90, an important protein chaperone, has been shown to be a…
Expand
2009
2009
Total synthesis of (-)-apratoxin A, 34-epimer, and its oxazoline analogue.
Y. Numajiri
,
Takashi Takahashi
,
T. Doi
Chemistry - An Asian Journal
2009
Corpus ID: 205445514
A concise and convergent total synthesis of the highly cytotoxic marine natural product apratoxin A is accomplished by an 18-step…
Expand
Highly Cited
2008
Highly Cited
2008
Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida.
Marcelino Gutiérrez
,
Takashi L Suyama
,
Niclas Engene
,
Joshua S. Wingerd
,
T. Matainaho
,
W. Gerwick
Journal of Natural Products
2008
Corpus ID: 21327698
Cancer cell toxicity-guided fractionation of extracts of the Papua New Guinea marine cyanobacteria Lyngbya majuscula and Lyngbya…
Expand
Highly Cited
2008
Highly Cited
2008
Apratoxin E, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium Lyngbya bouillonii.
S. Matthew
,
P. Schupp
,
H. Luesch
Journal of Natural Products
2008
Corpus ID: 27819893
A collection of the marine cyanobacterium Lyngbya bouillonii from Guam afforded apratoxin E (1), a new peptide-polyketide hybrid…
Expand
Highly Cited
2006
Highly Cited
2006
A functional genomics approach to the mode of action of apratoxin A
H. Luesch
,
S. Chanda
,
+5 authors
P. Schultz
Nature Chemical Biology
2006
Corpus ID: 19395841
The cyanobacterial metabolite apratoxin A (1) demonstrates potent cytotoxicity against tumor cell lines by a hitherto unknown…
Expand
Highly Cited
2004
Highly Cited
2004
Total synthesis of the marine cyanobacterial cyclodepsipeptide apratoxin A.
Jiehao Chen
,
C. Forsyth
Proceedings of the National Academy of Sciences…
2004
Corpus ID: 34697989
A total synthesis of apratoxin A was developed. Apratoxin A, isolated from Lyngbya spp. cyanobacteria, is representative of a…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE