defucogilvocarcin V

An efficient synthetic method for versatile dibenzoxaborins based on boron-selective Suzuki-Miyaura cross-coupling between o… (More)

Two enzymes of the gilvocarcin biosynthetic pathway, GilMT and GilM, with unclear functions were investigated by in vitro studies… (More)

The gene clusters responsible for the biosynthesis of two antitumor antibiotics, ravidomycin and chrysomycin, have been cloned… (More)

A key directed remote metalation (DreM)-carbamoyl migration strategy was applied in an efficient synthesis of the naturally… (More)

Gilvocarcin-type polyketide glycosides represent some of the most powerful antitumor therapeutics. Bioactivity-guided… (More)

The biosyntheses of the gilvocarcins (e.g., gilvocarcin V, 6, Scheme 1) and jadomycins (e.g., jadomycin B, 4) are both dominated… (More)

Resequencing of the gilGT gene, which encodes a putative glycosyltransferase (GT) that is 495 amino acids (aa) long, from the… (More)

In model studies towards the synthesis of gilvocarcin M, a convergent, xanthate-based free-radical strategy was tested in order… (More)

Gilvocarcin V, an antitumor agent produced by the bacterium Streptomyces griseoflavus Gö 3592, is the most studied representative… (More)

Very recently, ToMITA and coworkers' 2) have reported the fermentation, isolation and structure elucidation of gilvocarcins V (1… (More)