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declopramide

Known as: 3-Chloro-procainamide, 3-chloroprocainamide 
A substance that blocks the process cells use to repair DNA. It may help anticancer drugs and radiation kill more cancer cells. It is a type of… Expand
National Institutes of Health

Papers overview

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2012
2012
Objective: a new mutual prodrug was synthesized for colon targeting in the treatment of colon cancer associated with constipation… Expand
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2005
2005
Procainamide and related triethylamine-substituted 4-aminobenzamides, such as metoclopramide and declopramide, exert cellular… Expand
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Highly Cited
2004
Highly Cited
2004
Our laboratory has concentrated on the possible regulation the benzamides and nicotinamides may have on the processes of DNA… Expand
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2002
2002
We have analysed the mechanism of action for induction of apoptosis by N-substituted benzamides using declopramide as a lead… Expand
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2001
2001
N-substituted benzamides are compounds that have recently been reported to inhibit nuclear factor-kappaB (NF-kappaB) activity and… Expand
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1999
1999
Previous studies have suggested that some of the antitumor activity of declopramide (3-chloroprocainamide) could be due to its… Expand
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1999
1999
SummaryBenzamides have been in clinical use for many years in treatment against various disorders. A recent application is that… Expand
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1999
1999
Declopramide (3-chloroprocainamide) has been identified in previous studies as a representative of a new class of… Expand
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1997
1997
3-Chloroprocainamide (3-CPA), an analog of metoclopramide (MCA), dose-dependently inhibited tumor growth in scid mice xenografted… Expand
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1991
1991
In previous studies we had shown that procainamide is metabolized to reactive metabolites by activated leukocytes, and evidence… Expand
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