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dechloroethylifosfamide

Known as: 2-DClIF, 2-dechloroethylifosfamide, 2-amino-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazophosphorine-2-o-xide 
National Institutes of Health

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Broader (1)

Ifosfamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
WILDLIFE CONTRACEPTION: TARGETING THE OOCYTE
The USDA’s National Wildlife Research Center (NWRC) has successfully researched and developed a number of chemical and… 
Highly Cited
2005
Highly Cited
2005
Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity
Repeated administration of agents (e.g., cancer chemotherapy) that can cause drug-induced nephrotoxicity may lead to acute or… 
2005
2005
Role of GSTM1, GSTP1, and GSTT1 Gene Polymorphism in Ifosfamide Metabolism Affecting Neurotoxicity and Nephrotoxicity in Children
The aim of this study was to evaluate the impact of GSTM1, GSTT1, and GSTP1 gene polymorphism on urinary excretion of unchanged… 
2004
2004
Determination of the urinary excretion of ifosfamide and its phosphorated metabolites by phosphorus-31 nuclear magnetic resonance spectroscopy
SummaryPhosphorus-31 nuclear magnetic resonance spectroscopy was used to analyze urine samples obtained from patients treated… 
2001
2001
Population pharmacokinetics of ifosfamide and its 2- and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients
Abstract. The aim of this study was to develop a population pharmacokinetic model that could describe the pharmacokinetics of… 
Highly Cited
2000
Highly Cited
2000
Evidence of renal metabolism of ifosfamide to nephrotoxic metabolites.
1997
1997
Urinary excretion of ifosfamide, 4-hydroxyifosfamide, 3- and 2-dechloroethylifosfamide, mesna, and dimesna in patients on fractionated intravenous ifosfamide and concomitant mesna therapy
Abstract The oxazaphosphorine antineoplastic ifosfamide (IF) is metabolized by two different initial pathways: ring oxidation… 
1996
1996
e Characteristics of Polysilicon xide Grown in Pure N2O
This work reports on the characteristics of polysil- icon oxide grown in pure N20 (NzO-grown polyoxide). The obtained polyoxide… 
1996
1996
Nuclear magnetic resonance and high-performance liquid chromatography-nuclear magnetic resonance studies on the toxicity and metabolism of ifosfamide.
A combination of high-resolution nuclear magnetic resonance (NMR) and high-performance liquid chromatography (HPLC)-NMR… 
1992
1992
A new approach to the study of ifosfamide metabolism by the analysis of human body fluids with 31P nuclear magnetic resonance spectroscopy.
[31P] nuclear magnetic resonance spectroscopy was used to analyze body fluids from patients treated with ifosfamide (IF). This… 
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