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daunorubicinol

Known as: Daunomycinol, 13-dihydrodaunorubicin, Duborimycin 
An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Duborimycin exhibits cytotoxic activity through… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Altered pharmacokinetics of liposomal formulations of drugs can diminish toxicity and allow the administration of the… Expand
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Highly Cited
2001
Highly Cited
2001
Cyclosporine A (CsA) inhibits P-glycoprotein (Pgp)-mediated cellular export of anthracyclines at clinically achievable… Expand
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2000
2000
Cardiac effects of anthracyclines or their metabolites may include both the stimulation and inhibition of Ca(2+) release from… Expand
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1999
1999
Abstract DaunoXome is a liposome formulation containing daunorubicin (DM). Encapsulation of the drug in liposomes presents the… Expand
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1999
1999
DoxA is a cytochrome P-450 monooxygenase involved in the late stages of daunorubicin and doxorubicin biosynthesis that has a… Expand
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1997
1997
We recently determined the function of the gene product of Streptomyces sp. strain C5 doxA, a cytochrome P-450-like protein, to… Expand
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Highly Cited
1993
Highly Cited
1993
PURPOSE To determine the toxicities and maximum-tolerated dose of cyclosporine (CsA) administered with daunorubicin as a… Expand
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1993
1993
This study evaluated potential contributions of daunorubicin and its principle metabolite, daunorubicinol, to the cardiotoxicity… Expand
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1975
1975
9-Acetyl-4-methoxy-7,8,9,11-tetrahydroxy-6,7,9,11-tetrahydroxy-o-(3'-amino-2',3',6'-trideoxy-alpha-L-lyxohexopyranoside… Expand
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Highly Cited
1973
Highly Cited
1973
  • Keld Danø
  • Biochimica et biophysica acta
  • 1973
  • Corpus ID: 39696820
Abstract The mechanism of a previously reported decreased accumulation of daunomycin in resistant compared to wild-type Ehrlich… Expand
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