darinaparsin

Known as: clarinaparsin, DMAs(III)SG, S-(dimethylarsino)glutathione 
A small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2018
024620052018

Papers overview

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2015
2015
Prostate cancer is the leading cause of cancer-related death in men in the United States. A major cause of drug resistance in… (More)
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2014
2014
Darinaparsin (Dar; ZIO-101; S-dimethylarsino-glutathione) is a promising novel organic arsenical currently undergoing clinical… (More)
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2013
2013
Acute myeloid leukemia (AML) with inversion of chromosome 3 is characterized by overexpression of EVI1 and carries a dismal… (More)
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2013
2013
PURPOSE It was recently reported that the organic arsenic compound darinaparsin (DPS) is a cytotoxin and radiosensitizer of tumor… (More)
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2012
2012
PURPOSE Hypoxia is an important characteristic of the solid tumor microenvironment and constitutes a barrier for effective… (More)
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2009
2009
PURPOSE Darinaparsin, an organic arsenic, targets essential cell survival pathways. We determined the dose-limiting toxicity (DLT… (More)
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2009
2009
Here, we report on the organic arsenical darinaparsin (ZIO-101, S-dimethylarsino-glutathione) and its anti-myeloma activity… (More)
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2009
2009
Background Darinaparsin is a novel organic arsenic that reaches higher intracellular concentration with decreased toxicity… (More)
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2006
2006
BACKGROUND AND PURPOSE Although inorganic arsenite (As(III)) is toxic in humans, it has recently emerged as an effective… (More)
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2006
2006
Glutathione (GSH) plays an important role in the metabolism of arsenite and arsenate by generating arsenic-glutathione complexes… (More)
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