darbepoetin alfa

Known as: DARBEPOETIN ALFA,RECOMBINANT, Novel Erythropoiesis Stimulating Protein, Darbepoetin 
A recombinant analog of the endogenous cytokine erythropoietin, an erythropoiesis-stimulating protein. Due to the addition of two carbohydrate chains… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Patients with systolic heart failure and anemia have worse symptoms, functional capacity, and outcomes than those… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Anemia is associated with an increased risk of cardiovascular and renal events among patients with type 2 diabetes and… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Substantial evidence suggests that anemia is an independent risk factor for worse outcomes in patients with heart… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES This study sought to investigate whether darbepoetin alfa, an erythropoiesis-stimulating protein (ESP), improves… (More)
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Highly Cited
2007
Highly Cited
2007
AIMS Anaemia is common in chronic heart failure (CHF) and associated with worse outcome. This randomized, double-blind, placebo… (More)
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Review
2007
Review
2007
The distinct molecular structure of darbepoetin alfa, in both its amino acid sequence and its carbohydrate content, results in a… (More)
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Highly Cited
2006
Highly Cited
2006
Aims: Besides stimulating hematopoiesis, erythropoietin (EPO) protects against experimental ischemic injury in the heart. The… (More)
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Highly Cited
2006
Highly Cited
2006
Administration of human recombinant erythropoietin (EPO) at time of acute ischemic renal injury (IRI) inhibits apoptosis… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Experiments on human erythropoietin (EPO) demonstrated that there is a direct relationship between the sialic acid… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Patients receiving chemotherapy often develop anemia. Darbepoetin alfa (Aranesp(TM)) is an erythropoiesis-stimulating… (More)
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