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dactylolide

National Institutes of Health

Papers overview

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2019
2019
Zampanolide and dactylolide are microtubule-stabilizing polyketides possessing potent cytotoxicity towards a variety of cancer… Expand
2018
2018
Dactylolide and certain analogues are attractive targets for study due to their structural resemblance to zampanolide, a very… Expand
Highly Cited
2016
Highly Cited
2016
Whole chromosomal instability (CIN), manifested as unequal chromosome distribution during cell division, is a distinguishing… Expand
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2015
2015
Summary Bestmann ylide [(triphenylphosphoranylidene)ketene] acts as a chemical linchpin that links nucleophilic entities, such as… Expand
Review
2014
Review
2014
Zampanolide and its structural relative dactylolide are promising new tubulin-assembly agents with the potential to become new… Expand
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2013
2013
The solution conformation behavior of the macrolide core of microtubule-stabilizing agents (-)-zampanolide and (-)-dactylolide… Expand
Highly Cited
2012
Highly Cited
2012
Zampanolide and its less active analog dactylolide compete with paclitaxel for binding to microtubules and represent a new class… Expand
2010
2010
The development of an approach leading to the total synthesis of dactylolide is described. The key features of this route include… Expand
2008
2008
The total synthesis of (-)-dactylolide and formal synthesis of (-)-zampanolide via target oriented beta-C-glycoside formation is… Expand
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Highly Cited
2005
Highly Cited
2005
[reaction: see text] The development of an approach leading to the total synthesis of dactylolide is described. The key features… Expand