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dCTP deaminase activity

Known as: 5-methyl-dCTP deaminase activity, dCTP aminohydrolase activity, deoxycytidine triphosphate deaminase activity 
Catalysis of the reaction: dCTP + H2O = dUTP + NH3. [EC:3.5.4.13]
National Institutes of Health

Papers overview

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2016
2016
Exploiting nucleotide metabolism to improve cancer therapy : by targeting dUTPase, dCTPase and NUDT15
Synthetic nucleobaseand nucleoside-analogs have stood the test of time and remain a cornerstone in the treatment regimen against… 
2007
2007
Effects of tibolone and its metabolites on Angiopoietin-1, Tie-2 and tumor necrosis factor-α mRNA in Ishikawa cells
2007
2007
Effects of tibolone and its metabolites on Angiopoietin-1, Tie-2 and tumor necrosis factor-alpha mRNA in Ishikawa cells. Implication for tibolone's effects on the endometrium.
OBJECTIVE To determine the effect of 17beta-estradiol, medroxyprogesterone acetate, tibolone and tibolone metabolites on… 
2004
2004
Effect of tibolone and its metabolites on vascular endothelial growth factor isoforms 121 and 165 and thrombospondin-1 mRNA in Ishikawa cells
Objective To compare the mRNA expression of vascular endothelial growth factor (VEGF) 121 and 165 isoforms and thrombospondin-1… 
2002
2002
The oxidized pyrimidine ribonucleotide, 5-hydroxy-CTP, is hydrolyzed efficiently by the Escherichia coli recombinant Orf135 protein.
1997
1997
Hyperoxic increases in lung ICAM-1 mRNA are independent of TNF-alpha and IL-1 beta mRNA.
Hyperoxia-exposure results in neutrophil accumulation and edema in the exposed lung. Intercellular adhesion molecule-1 (ICAM-1… 
1997
1997
Chiral influences of feedback inhibition with dCTP on murine deoxycytidine kinase.
The inhibitory effects of 4 kinds of 2'-deoxy-L-nucleoside 5'-triphosphates, which are enantiomers of natural dNTPs, on murine… 
1992
1992
A sequence variation in intron 17B of the cystic fibrosis transmembrane conductance regulator gene
q31-q32), the most common to result in cystic fibrosis (CF) is aF508 (allele fre .. quency 70%) (Kerem, 1989). The significance… 
1988
1988
Search for multienzyme complexes of DNA precursor pathways in uninfected mammalian cells and in cells infected with herpes simplex virus type I
Confirmatory evidence for the existence of a multienzyme complex of DNA precursor pathways in mammalian cells was obtained. Using… 
1988
1988
72 RELATIONSHIP BETWEEN INTRAELLULAR dCTP/ARA-CTP RATIO AND CYTOTOXIC EFFECT OF ARA-C
The dCTP/ara-CTP ratio seem to be one of very important factors,in ara-C cytotoxicity. In confirmation of this hypothesis, we… 
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