d(CCATTAATGG)2 B-DNA decamer
National Institutes of Health
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The incorporation of synthetic nucleoside analogues into DNA duplexes provides a unique opportunity to probe both structure and…
Molecular dynamics simulations of the DNA duplex d(CCAACGTTGG)(2) were used to study the relationship between DNA sequence and…
The anticancer activity of cisplatin arises from its ability to bind covalently to DNA, forming primarily intrastrand cross‐links…
The enantiomers of the symmetric metallointercalator complex 1-Rh(MGP)2phi5+ [MGP = 4-(guanidylmethyl)-1,10-phenanthroline; phi…
The crystal structure of the decanucleotide d(CGCAATTGCG)2 has been solved by a combination of molecular replacement and heavy…
A complete relaxation matrix approach employing a matrix eigenvalue/eigenvector solution to the Bloch equations is used to…
Arabinosylcytosine (araC) is an important anticancer drug that has been shown to be misincorporated into DNA double helix. The…
The dodecadeoxynucleotide duplex d-(GCATTAATGC)2 has been prepared with all adenine bases replaced by 2-NH2-adenine. This…
Internucleotide phosphotriesters comprise an important class of DNA lesions produced by carcinogenic alkylating agents. To avoid…