cytoplasmic mRNA processing body

Known as: P-body, P body, cytoplasmic mRNP granule 
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
020406019852018

Papers overview

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Highly Cited
2009
Highly Cited
2009
In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in microRNA (miRNA)-mediated post… (More)
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Highly Cited
2008
Highly Cited
2008
Recent results indicate that nontranslating mRNAs in eukaryotic cells exist in distinct biochemical states that accumulate in P… (More)
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Highly Cited
2007
Highly Cited
2007
P bodies are cytoplasmic domains that contain proteins involved in diverse posttranscriptional processes, such as mRNA… (More)
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Highly Cited
2007
Highly Cited
2007
Processing bodies (P-bodies) are cytoplasmic RNA granules that contain translationally repressed messenger ribonucleoproteins… (More)
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Highly Cited
2006
Highly Cited
2006
In eukaryotes, a specialized pathway of mRNA degradation termed nonsense-mediated decay (NMD) functions in mRNA quality control… (More)
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Highly Cited
2005
Highly Cited
2005
The mRNA processing body (P-body) is a cellular structure that regulates gene expression by degrading cytoplasmic mRNA. The… (More)
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Highly Cited
2005
Highly Cited
2005
Translation and mRNA degradation are affected by a key transition where eukaryotic mRNAs exit translation and assemble an mRNP… (More)
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Highly Cited
2005
Highly Cited
2005
mRNP remodeling events required for the transition of an mRNA from active translation to degradation are currently poorly… (More)
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Highly Cited
2005
Highly Cited
2005
In animals, the majority of microRNAs regulate gene expression through the RNA interference (RNAi) machinery without inducing… (More)
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Highly Cited
2004
Highly Cited
2004
Through a poorly understood mechanism, tumors respond to radiation by secreting cytokines capable of inhibiting apoptosis in… (More)
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