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cyclophosphamide/doxorubicin/fluorouracil protocol

Known as: CDF, Cyclophosphamide-Adriamycin-Fluorouracil Regimen, Cyclophosphamide/Doxorubicin/Fluorouracil 
An abbreviation for a chemotherapy combination used alone or together with other therapies to treat breast cancer. It is also being studied in the… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

Antineoplastic Combined Chemotherapy ProtocolsCyclophosphamide
DoxorubicinDoxorubicin HydrochlorideFluorouracilPEGASE 02 regimen

Papers overview

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Highly Cited
2019
Highly Cited
2019
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts.
Cancer-associated fibroblasts (CAFs) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma… 
Review
2018
Review
2018
The biology and role of CD44 in cancer progression: therapeutic implications
CD44, a non-kinase transmembrane glycoprotein, is overexpressed in several cell types including cancer stem cells and frequently… 
Highly Cited
2016
Highly Cited
2016
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
Cancer-associated fibroblasts (CAFs) are a major cellular component of tumor microenvironment in most solid cancers. Altered… 
Highly Cited
2013
Highly Cited
2013
Mechano-transduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer associated fibroblasts
To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from different stages of breast cancer… 
Highly Cited
2010
Highly Cited
2010
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Much interest is currently focused on the emerging role of tumor-stroma interactions essential for supporting tumor progression… 
Highly Cited
2006
Highly Cited
2006
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.
PURPOSE We developed a multigene predictor of pathologic complete response (pCR) to preoperative weekly paclitaxel and… 
Highly Cited
2000
Highly Cited
2000
Regulation of E2F1 activity by acetylation
During the G1 phase of the cell cycle, an E2F–RB complex represses transcription, via the recruitment of histone deacetylase… 
Highly Cited
1999
Highly Cited
1999
Structure and ligand of a histone acetyltransferase bromodomain
Histone acetylation is important in chromatin remodelling and gene activation. Nearly all known histone-acetyltransferase (HAT… 
Highly Cited
1996
Highly Cited
1996
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
The adenoviral oncoprotein E1A induces progression through the cell cycle by binding to the products of the p300/CBP and… 
Highly Cited
1989
Highly Cited
1989
Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro
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