cyclin-dependent kinase 2

Known as: p33cdk2 Kinase, Cdc2 Related Protein Kinase, CDK2 Protein 
A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The application of fragment-based screening techniques to cyclin dependent kinase 2 (CDK2) identified multiple (>30) efficient… (More)
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2007
2007
Cyclin dependent kinases have emerged as important drug targets with a multitude of therapeutic potentials for their inhibitors… (More)
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2006
2006
Cyclin dependent kinases (CDKs) have appeared as an important drug targets over the years with diverse therapeutic potentials… (More)
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2006
2006
The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy… (More)
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2003
2003
OBJECTIVE To investigate the expressions of cyclin E, cyclin dependent kinase 2 (CDK-2) and cyclin-dependent kinase inhibitor p57… (More)
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2002
2002
Apoptosis is closely linked to proliferation. In this study we showed that inducing apoptosis in mouse mesangial cells with… (More)
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Highly Cited
2001
Highly Cited
2001
The function of the centrosomes to direct mitotic spindles is critical for accurate chromosome transmission to daughter cells… (More)
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1997
1997
Prostate cancer, like other types of cancer, is associated with the loss of cell cycle control, resulting in unregulated growth… (More)
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Highly Cited
1993
Highly Cited
1993
In mammalian cells inhibition of the cdc2 function results in arrest in the G2-phase of the cell cycle. Several cdc2-related gene… (More)
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1992
1992
The E2F transcription factor has been found in association with the cyclin A protein, and this complex accumulates during the S… (More)
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