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cyclic-guanylate-specific phosphodiesterase activity

Known as: c-di-GMP-specific phosphodiesterase activity, cyclic bis(3->5')diguanylate phosphodiesterase activity, c-di-GMP phosphodiesterase activity 
Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+). [EC:3.1.4.52, RHEA:24905]
National Institutes of Health

Papers overview

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2015
2015
BackgroundVibrio cholerae is a facultative pathogen that lives in the aquatic environment and the human host. The ability of V… 
2013
2013
ABSTRACT Vibrio cholerae, a noninvasive bacterium, colonizes the intestinal epithelium and secretes cholera toxin (CT), a potent… 
Review
2012
Review
2012
Although fluoxetine is useful in the treatment of major depression, 30–40 % of the patients do not respond to therapy. The… 
Highly Cited
2009
Highly Cited
2009
ABSTRACT Quorum sensing (QS), or cell-cell communication in bacteria, is achieved through the production and subsequent response… 
Highly Cited
2008
Highly Cited
2008
ABSTRACT Phosphorelay systems are important mediators of signal transduction during bacterial adaptation to new environments… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Differences in whole-genome expression patterns between the classical and El Tor biotypes of Vibrio cholerae O1 were… 
Highly Cited
2005
Highly Cited
2005
The newly recognized bacterial second messenger 3′,5′-cyclic diguanylic acid (cyclic diguanylate (c-di-GMP)) has been shown to… 
Highly Cited
2005
Highly Cited
2005
ABSTRACT The cyclic dinucleotide second messenger cyclic diguanylate (c-diGMP) has been implicated in regulation of cell surface… 
Highly Cited
2004
Highly Cited
2004
While studying virulence gene regulation in Vibrio cholerae during infection of the host small intestine, we identified VieA as a… 
Highly Cited
1998
Highly Cited
1998
ABSTRACT The iviVII gene of Vibrio cholerae was previously identified by a screen for genes induced during intestinal infection…