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Core fucosylation catalyzed by core fucosyltransferase (Fut8) contributes to the progressions of epithelial ovarian cancer (EOC… Expand Copper Transporter 1 (CTR1) is a homotrimeric membrane protein providing the main route of copper transport into eukaryotic cells… Expand BACKGROUND
Curcumin is a naturally occurring polyphenol which has been demonstrated to possess diverse biological activities. We… Expand Clear cell renal cell carcinoma (ccRCC) features a Von Hippel-Lindau mutation, associated with a hypoxia-inducible factor (HIF… Expand Neuroblastoma is frequently diagnosed at advanced stage disease and treatment includes high dose chemotherapy and surgery… Expand Adding platinum drugs to anthracycline/taxane (ANC-Tax)-based neoadjuvant chemotherapy (NAC) improves pathological complete… Expand Increased levels of intracellular copper stimulate angiogenesis in human umbilical vein endothelial cells (HUVECs). Copper… Expand Copper transporter 1 (CTR1) is a transmembrane protein that imports copper(i) into yeast and mammalian cells. Surprisingly, the… Expand Defects in intracellular accumulation of the antitumour drug cisplatin are a commonly observed feature in the cells selected for… Expand The high-affinity copper transporter 1 (Ctr1) is a highly conserved transmembrane protein that mediates the internalization of… Expand