connective tissue growth factor production
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Atrial fibrosis plays a pivotal role in the pathophysiology of heart failure (HF). The left atrium (LA) experiences greater… Expand Serotonin (5-hydroxytryptamine: 5-HT) is recognized as a neurotransmitter in the central nerve system and as a regulator of… Expand Cardiac fibrosis evolves from the cardiac hypertrophic state. In this respect, estrogen and estrogen receptor beta (ERβ) inhibit… Expand Objective: Leptin acts as a cardiac profibrotic factor. However, the mechanisms underlying this effect are unclear. Therefore, we… Expand CTGF (connective tissue growth factor) is widely regarded as an important amplifier of the profibrogenic action of TGF… Expand Pancreatitis is classified into acute pancreatitis (AP) and chronic pancreatitis (CP). Apelin, a small regulatory peptide, is the… Expand Inflammatory responses in the kidney lead to tubulointerstitial fibrosis, a common feature of chronic kidney diseases. Here we… Expand Asthma is characterized by airway inflammation, hyper-responsiveness and remodeling. Extracellular acidification is known to be… Expand PURPOSE
Connective tissue growth factor (CTGF) is induced by transforming growth factor-beta (TGF-β) after corneal wounding. This… Expand Connective tissue growth factor (CCN2) is a major pro-fibrotic factor that frequently acts downstream of transforming growth… Expand