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connective tissue activating peptide III

Known as: Connective Tissue-Activating Peptide III, Low-Affinity Platelet Factor IV, LA-PF4 
Connective tissue-activating peptide III (85 aa, ~9 kDa) is encoded by the human PPBP gene. This protein plays a role in mitogenesis, extracellular… 
National Institutes of Health

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22 relations
Alpha GranuleBiologic DevelopmentCentral Nervous SystemChemotaxis

Papers overview

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Highly Cited
2006
Highly Cited
2006
Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G.
The CXC chemokines platelet factor 4 (PF-4/CXCL4) and connective tissue-activating peptide III (CTAP-III) are released by… 
2000
2000
Stimulation of Cellular Sphingomyelin Import by the Chemokine Connective Tissue-activating Peptide III*
The selective import of phospholipids into cells could be mediated by proteins secreted from the cells into the extracellular… 
1999
1999
A cellulose-binding domain-fused recombinant human T cell connective tissue-activating peptide-III manifests heparanase activity.
The chemokine connective tissue-activating peptide (CTAP)-III, which belongs to the leukocyte-derived growth factor family of… 
Highly Cited
1995
Highly Cited
1995
CXC Chemokines Connective Tissue Activating Peptide-III and Neutrophil Activating Peptide-2 are Heparin/Heparan Sulfate-degrading Enzymes (*)
Heparan sulfate proteoglycans at cell surfaces or in extracellular matrices bind diverse molecules, including growth factors and… 
1994
1994
Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2.
The connective tissue-activating peptide III (CTAP-III), which is released from activated platelets, represents an inactive… 
Highly Cited
1991
Highly Cited
1991
Chemotactic Activity and Receptor Binding of Neutrophil Attractant/Activation Protein‐1 (NAP‐1) and Structurally Related Host Defense Cytokines: Interaction of NAP‐2 With the NAP‐1 Receptor
Neutrophil attractant/activation protein‐1 (NAP‐1) has sequence similarity to platelet factor‐4 (PF‐4) and to NAP‐2 (a truncated… 
1990
1990
Negative regulation of human megakaryocytopoiesis by human platelet factor 4 (PF4) and connective tissue-activating peptide (CTAP-III).
We have previously reported that human platelet factor 4 (PF4) and beta-thromboglobulin inhibit human megakaryocyte (meg) colony… 
1986
1986
Chemical synthesis and expression in yeast of a gene encoding connective tissue activating peptide-III. A novel approach for the facile assembly of a gene encoding a human platelet-derived mitogen.
A synthetic gene encoding the platelet-derived factor, connective tissue activating peptide-III (CTAP-III) (Castor, C.W., Miller… 
1985
1985
Connective tissue activation: stimulation of glucose transport by connective tissue activating peptide III.
Connective tissue activating peptide III (CTAP III), a human platelet derived growth factor, induced marked stimulation of 2… 
Highly Cited
1979
Highly Cited
1979
Connective tissue activation. XIV. Composition and actions of a human platelet autacoid mediator.
Connective tissue activating peptide-III (CTAP-III) isolated from human platelets is a potent mitogen for human connective tissue… 
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