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A convergent total synthesis of the siderophore coelichelin is described. The synthetic route also provided access to acetyl… Expand The emergence of antibiotic resistant microorganisms has led to an increased need for the discovery and development of novel… Expand ABSTRACT Iron is essential in many biological processes. However, its bioavailability is reduced in aerobic environments, such as… Expand Under iron limitation, the Gram-positive bacterium Streptomyces coelicolor A3(2) excretes three siderophores of the hydroxamate… Expand The nonribosomally produced hydroxamate siderophore coelichelin from Streptomyces coelicolor contains the nonproteinogenic amino… Expand ABSTRACT A gene cluster for the biosynthesis of a new small cyclic peptide, dubbed trichamide, was discovered in the genome of… Expand Siderophore-mediated iron acquisition has been well studied in many bacterial pathogens because it contributes to virulence. In… Expand Coelichelin is a new tetrapeptide siderophore from Streptomyces coelicolor originally discovered by gene sequence analysis… Expand Nature Chem. Biol. doi:10.1038/nchembio731 (2005) Finding natural compounds that have important medicinal properties has always… Expand A gene cluster for the non-ribosomal synthesis of a peptide of unknown structure has been identified in the partial genome… Expand