cocaine metabolic process

Known as: cocaine metabolism 
The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
024619792017

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2011
2011
Cocaine is a widely abused drug without a U.S. Food and Drug Administration-approved medication. There is a recognized, promising… (More)
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2008
2008
Cocaine is recognized as the most reinforcing of all drugs of abuse. There is no anticocaine medication available. The disastrous… (More)
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2004
2004
Female rats display a more robust behavioral response to acute cocaine administration than do male rats. However, a clear… (More)
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2003
2003
Previous studies showed that prolonged access to cocaine or heroin self-administration (long access, or LgA) produces an… (More)
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2003
2003
We present the first crystal structures of a human protein bound to analogs of cocaine and heroin. Human carboxylesterase 1 (hCE1… (More)
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2001
2001
Butyrylcholinesterase (BChE) is important in cocaine metabolism, but it hydrolyzes (-)-cocaine only one-two thousandth as fast as… (More)
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2000
2000
Cocaine N-demethylation to norcocaine was studied in human liver microsomes of different ages. Norcocaine was formed at a… (More)
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2000
2000
To determine whether cocaine-induced behavioral alterations are modulated by ovarian hormones, ovariectomized rats were randomly… (More)
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1999
1999
This study was conducted to characterize female behavioral response to acute 'binge' pattern cocaine administration (15 mg kg(-1… (More)
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1999
1999
The purpose of the current study is to determine whether sex differences in metabolism of cocaine (COC) exist that could… (More)
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