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cocaine metabolic process
The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral…
National Institutes of Health
Semantic Scholar uses AI to extract papers important to this topic.
Benzoic acid is not the only important product of accelerated metabolism of cocaine
Proceedings of the National Academy of Sciences
Corpus ID: 205279275
Xiabin Chen et al. (1) describe pioneering work with a modified drug-metabolizing enzyme, a butyrylcholinesterase (BChE) analog…
Modeling cocaine-induced alterations in organization and patterning of neocortical development using human pluripotent stem cells
Abigail A. Kindberg
Corpus ID: 18758524
Disorders of human neocortical development are particularly difficult to study by using animal models because of the marked…
Pharmacokinetic strategies for treatment of drug overdose and addiction.
Future medicinal chemistry
Corpus ID: 27231976
The pharmacokinetic treatment strategy targets the drug molecule itself, aiming to reduce drug concentration at the site of…
Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels
Serge H. Ahmed
Journal of neurochemistry
Corpus ID: 23881765
Previous studies showed that prolonged access to cocaine or heroin self‐administration (long access, or LgA) produces an…
Predominant pathway of cocaine metabolism unknown.
C. L. Williams
R. B. Parker
The American journal of emergency medicine
Corpus ID: 45738051
Alcohol interactions with benzodiazepines and cocaine.
Advances in alcohol & substance abuse
Corpus ID: 25124917
A rational management of alcoholic patients requires an understanding of alcohol interactions with other drugs. In this…
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