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cocaine metabolic process

Known as: cocaine metabolism 
The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Benzoic acid is not the only important product of accelerated metabolism of cocaine
  • S. CurryS. Coombs
  • Proceedings of the National Academy of Sciences
  • 2016
  • Corpus ID: 205279275
Xiabin Chen et al. (1) describe pioneering work with a modified drug-metabolizing enzyme, a butyrylcholinesterase (BChE) analog… 
2015
2015
Modeling cocaine-induced alterations in organization and patterning of neocortical development using human pluripotent stem cells
Disorders of human neocortical development are particularly difficult to study by using animal models because of the marked… 
Review
2012
Review
2012
Pharmacokinetic strategies for treatment of drug overdose and addiction.
  • D. Gorelick
  • Future Medicinal Chemistry
  • 2012
  • Corpus ID: 27231976
The pharmacokinetic treatment strategy targets the drug molecule itself, aiming to reduce drug concentration at the site of… 
Highly Cited
2003
Highly Cited
2003
Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels
Previous studies showed that prolonged access to cocaine or heroin self‐administration (long access, or LgA) produces an… 
1995
1995
Predominant pathway of cocaine metabolism unknown.
Review
1984
Review
1984
Alcohol interactions with benzodiazepines and cocaine.
  • A. Hoyumpa
  • Advances in Alcohol & Substance Abuse
  • 1984
  • Corpus ID: 25124917
A rational management of alcoholic patients requires an understanding of alcohol interactions with other drugs. In this… 
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