cocaine esterase

Known as: cocaine carboxylesterase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
024619922017

Papers overview

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2010
2010
Cocaine is considered to be the most addictive of all substances of abuse and mediates its effects by inhibiting monoamine… (More)
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2010
2010
The present study is the first to utilize bacterial cocaine esterase (CocE) to increase elimination of a lethal dose of cocaine… (More)
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2010
2010
Rhodococcal cocaine esterase (CocE) is an attractive potential treatment for both cocaine overdose and cocaine addiction. CocE… (More)
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2009
2009
Enhancing cocaine metabolism by administration of cocaine esterase (CocE) has been recognized as a promising treatment strategy… (More)
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2009
2009
STUDY OBJECTIVE Cocaine toxicity results in cardiovascular complications, seizures, and death and accounts for approximately 20… (More)
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2006
2006
There is no approved means to prevent the toxic actions of cocaine. Cocaine esterase (CocE) is found in a rhodococcal strain of… (More)
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2002
2002
Here we report the first structure of a cocaine-degrading enzyme. The bacterial esterase, cocE, hydrolyzes pharmacologically… (More)
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2002
2002
The bacterial cocaine esterase, cocE, hydrolyzes cocaine faster than any other reported cocaine esterase. Hydrolysis of the… (More)
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2000
2000
A strain of Rhodococcus designated MB1, which was capable of utilizing cocaine as a sole source of carbon and nitrogen for growth… (More)
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1998
1998
Cocaine addiction and overdose have long defied specific treatment. To provide a new approach, the high-activity catalytic… (More)
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