Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

cobinamide phosphate guanylyltransferase activity

Known as: CobU, AdoCbi kinase/AdoCbi-phosphate guanylyltransferase, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 
Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate. [EC:2.7.7.62, RHEA:22715]
National Institutes of Health

Related topics

Related topics

1 relation
adenosylcobinamide kinase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
One pathway can incorporate either adenine or dimethylbenzimidazole as an alpha-axial ligand of B12 cofactors in Salmonella enterica.
Corrinoid (vitamin B12-like) cofactors contain various alpha-axial ligands, including 5,6-dimethylbenzimidazole (DMB) or adenine… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
2007
2007
Nitrosyl-Cobinamide, a New and Direct Nitric Oxide–Releasing Drug Effective In Vivo
A limited number of nitric oxide (NO)-generating drugs are available for clinical use for acute and chronic conditions. Most of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2004
2004
Cobalamin speciation using reversed-phase micro-high-performance liquid chromatography interfaced to inductively coupled plasma mass spectrometry
Abstract Micro-high-performance liquid chromatography interfaced to inductively coupled plasma mass spectrometry was optimized… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2000
2000
Analysis of the adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase (CobU) enzyme of Salmonella typhimurium LT2. Identification of residue His-46 as the site of guanylylation.
CobU is a bifunctional enzyme involved in adenosylcobalamin (coenzyme B(12)) biosynthesis in Salmonella typhimurium LT2. In this… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table I
Highly Cited
1999
Highly Cited
1999
In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.
In Salmonella typhimurium, the CobU, CobS, CobT, and CobC proteins have been proposed to catalyze the late steps in… Expand
1998
1998
Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,.
The X-ray structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) from Salmonella… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
1995
1995
Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus.
A 6.4-kb region of a 6.8-kb BamHI fragment carrying Rhodobacter capsulatus genes involved in late steps of cobalamin synthesis… Expand
Highly Cited
1994
Highly Cited
1994
In vitro selection of RNA aptamers specific for cyanocobalamin.
RNA receptors (aptamers) capable of specifically binding cyanocobalamin (vitamin B12) have been isolated by in vitro selection… Expand
Highly Cited
1990
Highly Cited
1990
cobA function is required for both de novo cobalamin biosynthesis and assimilation of exogenous corrinoids in Salmonella typhimurium.
Salmonella typhimurium is able to synthesize cobalamin (B12) under anaerobic growth conditions. The previously described… Expand
1971
1971
Assignments in the carbon-13 nuclear magnetic resonance spectra of vitamin B12' coenzyme B12' and other corrinoids: application of partially-relaxed fourier transform spectroscopy.
High-resolution Fourier transform NMR at 15.08 MHz was used to observe the proton-decoupled natural-abundance (13)C spectra of… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE