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coagulation factor X, human

Known as: Stuart Factor, Blood Coagulation Factor X, Factor X 
Coagulation factor X (488 aa, ~55 kDa) is encoded by the human F10 gene. This protein is involved in proteolysis and blood coagulation.
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Significance The generation of thrombin by prothrombinase, a complex composed of activated (a) factors X (FXa) and V (FVa), is a… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Microparticles (MPs) are sub-micron vesicles shed by activated or apoptotic cells, including platelets and monocytes… Expand
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Highly Cited
2007
Highly Cited
2007
Thrombin, a central mediator of hemostasis and thrombosis, converts fibrinogen to fibrin and is a potent platelet activator… Expand
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Highly Cited
2003
Highly Cited
2003
Fibrin deposition and thrombosis within the microvasculature is now appreciated to play a pivotal role in the hepatocellular… Expand
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Highly Cited
2002
Highly Cited
2002
Tissue factor-induced blood coagulation was studied in 20 individuals, for varying periods of time during 54 months, in contact… Expand
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Highly Cited
2000
Highly Cited
2000
ATP-binding-cassette transporter 1 (ABC1) has been implicated in processes related to membrane-lipid turnover. Here, using in… Expand
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Review
1999
Review
1999
PROBLEM Maternal "rejection" of the implanted conceptus is considered to account for a significant proportion of miscarriages… Expand
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Highly Cited
1993
Highly Cited
1993
Investigation of red blood cells from beta-thalassemia patients by means of prothrombinase assay reveals phosphatidylserine in… Expand
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Highly Cited
1990
Highly Cited
1990
The role of calcium and intracellular calpains in the expression of platelet prothrombinase activity was investigated. Incubation… Expand
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Highly Cited
1989
Highly Cited
1989
Activation of human platelets by complement proteins C5b-9 is accompanied by the release of small plasma membrane vesicles… Expand
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