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clusterin antisense oligonucleotide

Known as: (3'-5')d(P-thio)([2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2- methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rC-A-G-C-A-G-A-G-T-C-T-T-C-A-[2'-O-(2- methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2- methoxyethyl)]m5rU), Eicosasodium Salt, CUSTIRSEN SODIUM 
The eicosasodium salt of a mixed-backbone antisense oligodeoxynucleotide with chemosensitizing properties. Custirsen inhibits testosterone-repressed… 
National Institutes of Health

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OGX-011

Papers overview

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2013
2013
CRPC: Neuer Behandlungsansatz kann Therapieresistenz verzögern
— Obwohl viele Patienten mit kastrationsresistentem Prostatakarzinom (CRPC) zunächst gut auf eine antiandrogene Behandlung oder… 
2013
2013
Kombinationstherapie wirksam gegen BPS-Komplikationen
— Obwohl viele Patienten mit kastrationsresistentem Prostatakarzinom (CRPC) zunächst gut auf eine antiandrogene Behandlung oder… 
2008
2008
Clusterin antisense complexed with chitosan for controlled intratumoral delivery.
2005
2005
Efficacy of an intratumoral controlled release formulation of clusterin antisense oligonucleotide complexed with chitosan containing paclitaxel or docetaxel in prostate cancer xenograft models
PurposeTo develop and evaluate an injectable, controlled release delivery system for a phosphorothioate antisense oligonucleotide… 
2004
2004
Modulation of Clusterin Isoforms Is Associated With All-Trans Retinoic Acid–Induced Proliferative Arrest and Apoptosis of Intimal Smooth Muscle Cells
Objectives— Clusterin is a heterodimeric glycoprotein which is implicated in several biological processes. The nuclear (n-CLU… 
1999
1999
An intratumoral controlled release formulation of clusterin antisense oligonucleotide and paclitaxel or docetaxel for treatment of prostate tumors
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