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clofoctol
Known as:
Phenol, 2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-
, octofene
A bacteriostatic antibiotic with activity against Gram-positive bacteria. Clofoctol is used in the treatment of upper and lower respiratory tract…
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Cresols
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Identification and Ranking of Clinical Compounds with Activity against Log-phase Growing Uropathogenic Escherichia coli.
Hongxia Niu
,
R. Yee
,
+7 authors
Ying Zhang
Current Drug Discovery Technologies
2020
Corpus ID: 51934253
BACKGROUND Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infections (UTIs). Due to increasing…
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2019
2019
Comparative Emergence of Resistance to Clofoctol, Erythromycin, and Amoxicillin against Community-Acquired Bacterial Respiratory Tract Pathogens in Italy
F. Scaglione
,
V. Lucini
,
S. Dugnani
,
A. Pani
Chemotherapy
2019
Corpus ID: 85514806
Due to increasing bacterial resistance and poor availability of new antibiotics, physicians need to use old, still active…
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1988
1988
A pharmacokinetic study of clofoctol in human plasma and lung tissue by using a microbiological assay.
R. Danesi
,
M. Gasperini
,
S. Senesi
,
G. Freer
,
C. Angeletti
,
M. del Tacca
Drugs under experimental and clinical research
1988
Corpus ID: 45641835
A microbiological assay was undertaken to measure the amounts of clofoctol in human plasma and pulmonary tissue, and to…
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1987
1987
Penetration of clofoctol into human lung.
M. del Tacca
,
R. Danesi
,
S. Senesi
,
M. Gasperini
,
A. Mussi
,
C. Angeletti
Journal of Antimicrobial Chemotherapy
1987
Corpus ID: 1917120
The disposition of clofoctol was determined in plasma and lung tissue from 34 patients undergoing pulmonary resection for lung…
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1986
1986
The pharmacokinetic profile of clofoctol in rat plasma and tissues after oral and rectal administration.
M. Alessandrì
,
M. Ducci
,
+4 authors
L. Mazzanti
Drugs under experimental and clinical research
1986
Corpus ID: 10731204
The pharmacokinetics of clofoctol was investigated in rat plasma and tissues after both oral and rectal treatment at a single…
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1985
1985
Clinical study on the efficacy of clofoctol in the treatment of infectious respiratory diseases.
R. Danesi
,
M. del Tacca
International journal of clinical pharmacology…
1985
Corpus ID: 29593673
The effectiveness and the safety of a new chemotherapeutic phenol derivative, clofoctol, was evaluated in adult hospitalized…
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1985
1985
Treatment of ear, nose and throat infections with clofoctol.
P. Ghilardi
,
A. Casani
Drugs under experimental and clinical research
1985
Corpus ID: 40826078
Fifty-two adult patients affected by infectious otorhinolaryngological diseases were treated rectally with clofoctol, a new…
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1984
1984
New information on the antibacterial activity of clofoctol
A. Buogo
1984
Corpus ID: 88556288
1983
1983
The pharmacokinetics of clofoctol in healthy neonates and adults studied by an original HPLC technique.
M. del Tacca
,
M. Ducci
,
G. Soldani
,
A. Boldrini
,
M. Fantoni
,
A. Bertelli
Biological research in pregnancy and perinatology
1983
Corpus ID: 20944638
The pharmacokinetics of clofoctol [(tetramethyl-1,1,3,3,butyl)-4-(dichloro-2,4-benzyl)-2-hydroxy-1-benzene ] was investigated in…
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1982
1982
Action of clofoctol on bacterial cell wall synthesis.
F. Yablonsky
,
G. Simonnet
Journal de pharmacologie
1982
Corpus ID: 698323
Clofoctol inhibits in vivo cell wall synthesis of B. subtilis and gives rise to an accumulation of UDP-N-acetyl-muramyl…
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