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clavam

National Institutes of Health

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Clavulanic Acids

Papers overview

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2006
2006
CLAVAMYCINS, NEW CLAVAM ANTIBIOTICS FROM TWO VARIANTS OF STREPTOMYCES HYGROSCOPICUS II. ISOLATION AND STRUCTURES OF CLAVAMYCINS A, B AND C FROM STREPTOMYCES HYGROSCOPICUS NRRL 15846, AND OF…
  • Nrrl
  • 2006
  • Corpus ID: 46967889
In the preceding reportl1), taxonomy of the producing strains, fermentation and biological activities of new clavam antibiotics… 
Highly Cited
2005
Highly Cited
2005
The enzymology of clavam and carbapenem biosynthesis.
The enzyme-catalysed reactions involved in formation of the bicyclic clavam and carbapenem nuclei, including beta-amino acid and… 
2004
2004
Streptomyces clavuligerus Has a Second Copy of the Proclavaminate Amidinohydrolase Gene
ABSTRACT Past genetic studies have indicated that the genes encoding early enzymes of clavulanic acid biosynthesis may be… 
2001
2001
Applications of Gene Replacement Technology toStreptomyces clavuligerus Strain Development for Clavulanic Acid Production
ABSTRACT Cephamycin C production was blocked in wild-type cultures of the clavulanic acid-producing organism Streptomyces… 
Review
2000
Review
2000
Clavulanic acid, a beta-lactamase inhibitor: biosynthesis and molecular genetics.
Clavulanic acid is a secondary metabolite produced by Streptomyces clavuligerus. It possesses a clavam structure and a… 
Review
1999
Review
1999
Class A beta-lactamases--enzyme-inhibitor interactions and resistance.
Beta-Lactamases of Ambler's Class A are the most commonly encountered mechanism of bacterial resistance to beta-lactam… 
1997
1997
[Antitumor activity of the clavam peptide antibiotic G0069A].
Antibiotic G0069A, produced by a Streptomyces strain isolated from a soil sample collected in Yunnan Province, China, has been… 
1993
1993
Emerging evidence for a shared biosynthetic pathway among clavulanic acid and the structurally diverse clavam metabolites
1986
1986
A process for the preparation of clavam novel, are useful for the preparation of clavulanic acid, and intermediates thereof.
A process for the preparation of novel clavam, useful for the preparation of clavulanic acid, intermediate and THEREOF. NEW… 
1983
1983
Ro 22-5417, a new clavam antibiotic from Streptomyces clavuligerus. III. Absolute stereochemistry.
The complete stereostructure of the new antibiotic Ro 22-5417 has been established as 3-[(3S,5S)-7-oxo-1-aza-4-oxabicyclo[3.2.O… 
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