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cisplatin/flavopiridol/paclitaxel
Known as:
CDDP/FLAVO/TAX
National Institutes of Health
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Related topics
Related topics
4 relations
Alvocidib Hydrochloride
Cisplatin
Flavopiridol
Paclitaxel
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
G2/M inhibitors as pharmacotherapeutic opportunities for glioblastoma: the old, the new, and the future
A. M. Castro-Gamero
,
J. Pezuk
,
M. Brassesco
,
L. Tone
Cancer Biology and Medicine
2018
Corpus ID: 61809317
Glioblastoma (GBM) is one of the deadliest tumors and has a median survival of 3 months if left untreated. Despite advances in…
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2013
2013
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells
M. Pallis
,
F. Burrows
,
Abigail Whittall
,
N. Boddy
,
C. Seedhouse
,
N. Russell
BMC Pharmacology and Toxicology
2013
Corpus ID: 6958420
BackgroundDormant cells are characterised by low RNA synthesis. In contrast, cancer cells can be addicted to high RNA synthesis…
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Review
2012
Review
2012
Mechanism of Nitric Oxide Synthase Regulation: Electron Transfer and Interdomain Interactions.
Changjian Feng
Coordination chemistry reviews
2012
Corpus ID: 36849785
2012
2012
Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl+ hematological malignancies
P. Bose
,
E. Perkins
,
+15 authors
S. Grant
Cancer Chemotherapy and Pharmacology
2012
Corpus ID: 19603509
PurposeImatinib is an inhibitor of the Bcr-Abl tyrosine kinase; however, resistance is common. Flavopiridol, a cyclin-dependent…
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2010
2010
A Phase I Study of Flavopiridol in Combination With Gemcitabine and Irinotecan in Patients With Metastatic Cancer
H. M. Fekrazad
,
C. Verschraegen
,
M. Royce
,
H. Smith
,
Fa Chyi Lee
,
I. Rabinowitz
American Journal of Clinical Oncology
2010
Corpus ID: 205561527
Background:Flavopiridol (HMR 1275) is a synthetic flavone with antineoplastic properties through inhibition of cyclin-dependent…
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Review
2007
Review
2007
Zebrafish as a Model System to Screen Radiation Modifiers
M. Hwang
,
Cha Yong
,
L. Moretti
,
B. Lu
Current Genomics
2007
Corpus ID: 8342813
Zebrafish (Danio rerio) is a bona fide vertebrate model system for understanding human diseases. It allows the transparent…
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2003
2003
Flavopiridol-related proinflammatory syndrome is associated with induction of interleukin-6.
R. Messmann
,
C. D. Ullmann
,
+8 authors
A. Senderowicz
Clinical Cancer Research
2003
Corpus ID: 402148
BACKGROUND Flavopiridol is a flavonoid with antiproliferative effects mediated, in part, by inhibition of cyclin-dependent…
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2002
2002
Current Clinical Trials of Flavopiridol
A. Colevas
,
B. Blaylock
,
A. Gravell
2002
Corpus ID: 30839603
Flavopiridol [2-(2-chlorophenyl 5 ,7-dihydroxy-8-[cis-(3-hydroxy-1-methyl-4-piperidinyl)-4H-1-benzopyran-4-one, hydrochloride] is…
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Highly Cited
2000
Highly Cited
2000
Flavopiridol binds to duplex DNA.
K. Bible
,
R. Bible
,
+5 authors
S. Kaufmann
Cancer Research
2000
Corpus ID: 18954822
Flavopiridol, the first potent cyclin-dependent kinase inhibitor to enter clinical trials, was recently found to be cytotoxic to…
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Highly Cited
1999
Highly Cited
1999
Solubilization of flavopiridol by pH control combined with cosolvents, surfactants, or complexants.
P. Li
,
S. Tabibi
,
S. Yalkowsky
Journal of Pharmacy and Science
1999
Corpus ID: 10198212
This study investigates the roles of both ionized and un-ionized species of flavopiridol in solubilization by complexation…
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