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cis-2-butene-1,4-dial

 
National Institutes of Health

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2012
2012
Furan is a liver toxicant and carcinogen in rodents. It is classified as a possible human carcinogen, but the human health… Expand
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2010
2010
Furan is a rodent hepatotoxicant and carcinogen. Because this compound is an important industrial intermediate and has been… Expand
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2008
2008
Furan is found in various food items and is cytotoxic and carcinogenic in the liver of rats and mice. Metabolism of furan… Expand
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2006
2006
Furan is a toxic and carcinogenic compound used in industry and commonly found in the environment. The mechanism of furan's… Expand
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2006
2006
The hepatocarcinogen and toxicant furan requires metabolic activation to elicit its toxic effects. The available experimental… Expand
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2005
2005
Furan is a liver carcinogen and toxicant. Furan is oxidized to the reactive dialdehyde, cis-2-butene-1,4-dial, by microsomal… Expand
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2002
2002
Furan is a hepatic toxicant and carcinogen in rodents. Its microsomal metabolite, cis-2-butene-1,4-dial, is mutagenic in the Ames… Expand
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2000
2000
Furan is classified as a nongenotoxic hepatocarcinogen. It is thought to be activated to a toxic metabolite, cis-2-butene-1,4… Expand
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1997
1997
Metabolic activation of the hepatocarcinogen furan yields metabolites that react covalently with proteins. cis-2-Butene-1,4-dial… Expand
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1995
1995
The hepatocarcinogen furan is believed to be activated to the reactive aldehyde, cis-2-butene-1,4-dial, by microsomal enzymes… Expand
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