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ciclopirox

Known as: Ciclopiroxum, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone, ciclopirox [Chemical/Ingredient] 
A synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

Antifungal AgentsPyridones

Narrower (5)

BatrafenCiclopirox olamineDafnegin-CSCHOE 296
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Cutaneous CandidiasisDecreased Protein Synthesis [PE]HypersensitivityOnychomycosis
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
Reactive oxygen species- (ROS-) induced lipid peroxidation plays a critical role in cell death including apoptosis, autophagy… 
Review
2012
Review
2012
Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment.
Highly Cited
2009
Highly Cited
2009
An innovative water‐soluble biopolymer improves efficacy of ciclopirox nail lacquer in the management of onychomycosis
Background  A new 8% ciclopirox‐medicated nail lacquer (P‐3051), based on a new technology, revealed superior properties in terms… 
Review
2005
Review
2005
Topical antifungal drugs for the treatment of onychomycosis: an overview of current strategies for monotherapy and combination therapy
Background  Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders and its prevalence rises… 
Highly Cited
2003
Highly Cited
2003
In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity
Summary  Background With the development of newer antifungal agents with activity against both yeasts and filamentous fungi… 
Highly Cited
2000
Highly Cited
2000
Ciclopirox nail lacquer topical solution 8% in the treatment of toenail onychomycosis.
BACKGROUND Onychomycosis is a relatively common condition affecting toenails more than fingernails. It is caused predominantly by… 
Highly Cited
2000
Highly Cited
2000
Onychomycosis caused by nondermatophytic molds: clinical features and response to treatment of 59 cases.
Highly Cited
1997
Highly Cited
1997
In‐vitro Permeability of the Human Nail and of a Keratin Membrane from Bovine Hooves: Prediction of the Penetration Rate of Antimycotics through the Nail Plate and their Efficacy
In contrast to the partition coefficient octanol/water the molecular size of penetrating drugs has a noticeable influence on the… 
Highly Cited
1996
Highly Cited
1996
Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support
In the present study, we tested whether apoptotic neuronal death caused by withdrawal of trophic support might be prevented by… 
Review
1992
Review
1992
Terbinafine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in superficial mycoses.
Terbinafine is an orally and topically active allylamine antifungal agent with a primarily fungicidal action in vitro. Its… 
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