ciclopirox

Known as: Ciclopiroxum, 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone, ciclopirox [Chemical/Ingredient] 
A synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding… (More)
National Institutes of Health

Papers overview

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2013
2013
Ciclopirox, an antifungal agent commonly used for the dermatologic treatment of mycoses, has been shown recently to have… (More)
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2009
2009
Eukaryotic translation initiation factor eIF5A has been implicated in HIV-1 replication. This protein contains the apparently… (More)
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2009
2009
Transungual delivery of antifungal drugs is hindered by the low permeability of human nail plates, and as such, repeated dosing… (More)
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Review
2008
Review
2008
Treatment of dermatophyte infection involves primarily oral and/or topical formulations of azoles or allylamines, particularly… (More)
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2005
2005
BACKGROUND Treatment of onychomycosis has recently been enhanced by the introduction of combination therapies. OBJECTIVE To… (More)
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2005
2005
1 The mitochondrial respiratory chain produces reactive oxygen species (ROS) during normal electron transport. Despite producing… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND With the development of newer antifungal agents with activity against both yeasts and filamentous fungi, there is an… (More)
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2002
2002
The hypusine biosynthetic steps represent novel targets for intervention in cell proliferation. Hypusine is a rare amino acid… (More)
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Review
2000
Review
2000
Ciclopirox is a synthetic hydroxypyridone antifungal agent. In contrast to the azoles, glucuronidation is the main metabolic… (More)
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Highly Cited
1996
Highly Cited
1996
In the present study, we tested whether apoptotic neuronal death caused by withdrawal of trophic support might be prevented by… (More)
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