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chuangxinmycin

Known as: 2H-Thiopyrano(4,3,2-cd)indole-2-carboxylic acid, 3,5-dihydro-3-methyl-, cis-(-)- 
National Institutes of Health

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Papers overview

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2019
2019
Synthesis, resolution, derivatization and antibacterial activity of chuangxinmycin.
Aim: An urgent need for the development of antibiotics with novel structures and unexploited targets. Materials & methods… 
2018
2018
Heterologous Expression Guides Identification of the Biosynthetic Gene Cluster of Chuangxinmycin, an Indole Alkaloid Antibiotic.
The indole alkaloid antibiotic chuangxinmycin, from Actinobacteria Actinoplanes tsinanensis, containing a unique thiopyrano[4,3,2… 
2018
2018
Biosynthesis of antibiotic chuangxinmycin from Actinoplanes tsinanensis
2010
2010
Regulation of an Auxiliary, Antibiotic-Resistant Tryptophanyl-tRNA Synthetase Gene via Ribosome-Mediated Transcriptional Attenuation
ABSTRACT cis-Acting RNA elements in the leaders of bacterial mRNA often regulate gene transcription, especially in the context of… 
2008
2008
Characterization of an Inducible, Antibiotic-Resistant Aminoacyl-tRNA Synthetase Gene in Streptomyces coelicolor
ABSTRACT Streptomyces coelicolor has two genes encoding tryptophanyl-tRNA synthetases, one of which (trpRS1) is resistant to and… 
Highly Cited
2002
Highly Cited
2002
The antimicrobial natural product chuangxinmycin and some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase.
2001
2001
Improved preparation of sulfur substituted 3-vinylpyrrole and its application to the syntheses of chuangxinmycin derivatives.
Sulfur substituted 3-vinylpyrrole 10 was prepared from 3-thio-acetylpyrrole 9 by alkylation with alkyl halide in the presence of… 
1987
1987
Nitration of 3-acylindoles in the presence of metal MeCN solvates and synthesis of the antibiotic alkaloid chuangxinmycin.
Nitration of 3-acylindoles in the presence of MeCN solvates of Cu2+, Al3+, and Fe2+ salts yielded 3-nitroindole, 4-nitro-and 6… 
Review
1979
Review
1979
Members of the genus Actinoplanes and their antibiotics.
INTRODUCTION ....... . GENERAL DESCRIPTION OF THE GENUS . . . . . . . . . Sporangia Morphology and Spore Formation… 
1977
1977
Studies on a new antibiotic--Chuangxinmycin.
  • Scientia Sinica
  • 1977
  • Corpus ID: 44489155
A new antibiotic, designated Chuangxinmycin and produced by a new species of microorganism Actinoplanes tsinanensis n. sp., has… 
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