chronic depression

Although several studies have examined the effects of psychotherapy on chronic depression and dysthymia, no meta-analysis has… (More)

This pilot study investigated the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT), a treatment combining mindfulness… (More)

BACKGROUND Elevated phosphorylation of neurotrophin-regulated transcription factors, such as cyclic adenosine monophosphate (cAMP… (More)

BACKGROUND Hypothalamic-pituitary-adrenal (HPA) axis function in patients with chronic depression has previously been shown to be… (More)

BACKGROUND Patients with chronic forms of major depression are difficult to treat, and the relative efficacy of medications and… (More)

OBJECTIVE The authors examined gender differences in treatment response to sertraline, a selective serotonin reuptake inhibitor… (More)

OBJECTIVE Chronic depression starts at an early age for many individuals and could affect their accumulation of "human capital… (More)

Depression has been associated with both suppression and enhancement of various aspects of immune functioning. It was of interest… (More)

BACKGROUND Previous research has suggested that depressed patients, and particularly chronically depressed patients, have… (More)

BACKGROUND AND PURPOSE This prospective study was designed to examine the contributions of neurobiological, functional, and… (More)