FAQ

chromosome, centromeric region

Known as: centromere complex, centromere complex location, chromosome, centric region 
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single… (More)

Topic mentions per year

Topic mentions per year

1993-2017
02419932017

Related topics

Related topics

5 relations

Narrower (3)

CBF3 complexCentric heterochromatinKinetochores
Centromerechromatin silencing at centromere

Related mentions per year

Related mentions per year

1940-2018
19401960198020002020
chromosome, centromeric region
Centromere
Kinetochores
Centric heterochromatin
CBF3 complex
chromatin silencing at centromere

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis.
Centromeres are chromatin domains specified by nucleosomes containing the histone H3 variant, CENP-A. This unique centromeric… (More)
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2017
2017
CENPH Inhibits Rapamycin Sensitivity by Regulating GOLPH3-dependent mTOR Signaling Pathway in Colorectal Cancer
Background: Centromere protein H (CENPH) is known as a fundamental component of the active centromere complex, and its… (More)
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2014
2014
Bacterial scaffold directs pole-specific centromere segregation.
Bacteria use partitioning systems based on the ParA ATPase to actively mobilize and spatially organize molecular cargoes… (More)
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Review
2012
Review
2012
Temporal control of epigenetic centromere specification
All living organisms require accurate mechanisms to faithfully inherit their genetic material during cell division. The… (More)
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2009
2009
Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function.
We previously identified cancer-upregulated gene 2 (CUG2) as a commonly up-regulated gene in various human cancer tissues… (More)
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2009
2009
CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis.
OBJECTIVE CENP-A, -B, and -C are major centromere components and the main targets of anticentromere antibodies (ACA). Many other… (More)
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Highly Cited
2006
Highly Cited
2006
Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.
The centromere is a chromatin structure essential for correct segregation of sister chromatids, and defects in this region often… (More)
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Highly Cited
2004
Highly Cited
2004
Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the…
CENP-A, a centromere-specific histone H3, is conserved throughout eukaryotes, and formation of CENP-A chromatin defines the… (More)
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Highly Cited
2004
Highly Cited
2004
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1
Defects in kinetochore proteins often lead to aneuploidy and cancer. Mis12–Mtw1 is a conserved, essential kinetochore protein… (More)
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1993
1993
Cpf1 protein induced bending of yeast centromere DNA element I.
The centromere complex is a multicomponent structure essential for faithful chromosome transmission. Here we show that the S… (More)
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