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chromium mesoporphyrin

Known as: CrMP compound, chromium-mesoporphyrin 
 
National Institutes of Health

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Mesoporphyrins

Papers overview

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2009
2009
Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats.
Insulin-mediated signal transduction is positively correlated to adiponectin, adenosine monophosphate-activated protein kinase… Expand
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2009
2009
Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes.
Hyperglycemia-induced oxidative stress is a common phenomenon in diabetes. Since oxidative stress depletes adiponectin and… Expand
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2006
2006
Rat mesenteric arterial dilator response to 11,12-epoxyeicosatrienoic acid is mediated by activating heme oxygenase.
11,12-Epoxyeicosatrienoic acid (11,12-EET), a potent vasodilator produced by the endothelium, acts on calcium-activated potassium… Expand
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Highly Cited
2002
Highly Cited
2002
Selective regulation of blood pressure by heme oxygenase-1 in hypertension.
Heme oxygenase (HO) and carbon monoxide (CO) participate in the homeostatic control of cardiovascular functions, including the… Expand
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Highly Cited
2001
Highly Cited
2001
Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors.
Rat renal interlobar arteries express heme oxygenase 2 (HO-2) and manufacture carbon monoxide (CO), which is released into the… Expand
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Highly Cited
1999
Highly Cited
1999
Carbon monoxide and cerebral microvascular tone in newborn pigs.
The present study addresses the hypothesis that CO produced from endogenous heme oxygenase (HO) can dilate newborn cerebral… Expand
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Highly Cited
1999
Highly Cited
1999
Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations.
Studies on the physiological role of heme oxygenase (HO) require an inhibitor that will selectively inhibit HO activity without… Expand
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Highly Cited
1999
Highly Cited
1999
Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels.
Endogenous carbon monoxide was proposed to subserve vasodepressor functions. If so, inhibition of heme oxygenase may be expected… Expand
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Highly Cited
1994
Highly Cited
1994
Inhibition of hippocampal heme oxygenase, nitric oxide synthase, and long-term potentiation by metalloporphyrins
Four potent metalloporphyrin inhibitors of heme oxygenase were used to assess whether carbon monoxide production was required for… Expand
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Highly Cited
1993
Highly Cited
1993
Selection of Metalloporphyrin Heme Oxygenase Inhibitors Based on Potency and Photoreactivity
ABSTRACT: The heme oxygenase inhibitor, tin protoporphyrin, is being studied for the prevention of neonatal jaundice. This… Expand
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