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cholesterol 7-alpha-monooxygenase activity

Known as: cholesterol 7-alpha-hydroxylase activity, cholesterol 7alpha-hydroxylase activity, cholesterol 7alpha-monooxygenase activity 
Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O. [EC:1.14.13.17]
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Plant sterols compete with cholesterol (cholest-5-en-3beta-ol) for intestinal absorption to limit absorption and lower plasma… Expand
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Highly Cited
2002
Highly Cited
2002
The effects of taurine on hepatic cholesterol metabolism were investigated in hamsters fed a high-fat diet or normal chow. Two… Expand
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Highly Cited
2001
Highly Cited
2001
A tocotrienol-rich fraction (TRF(25)) and novel tocotrienols (d-P(21)-T3 and d-P(25)-T3) of rice bran significantly lowered serum… Expand
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Highly Cited
2000
Highly Cited
2000
Fibrates are widely used hypolipidemic drugs that regulate the expression of many genes involved in lipid metabolism by… Expand
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Highly Cited
1999
Highly Cited
1999
Acyl‐coenzyme A:cholesterol acyltransferase (ACAT) inhibitors are currently in clinical development as potential lipid‐lowering… Expand
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1999
1999
The regulation of the classic and alternative bile acid synthetic pathways by key hepatic enzyme activities (microsomal… Expand
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Review
1999
Review
1999
  • J. Cohen
  • Current opinion in lipidology
  • 1999
  • Corpus ID: 23205682
Clinical studies have clearly established a relationship between bile acid synthesis and plasma LDL-cholesterol concentrations… Expand
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1999
1999
We investigated the effect of increasing dietary cholesterol on bile acid pool sizes and the regulation of the two bile acid… Expand
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Highly Cited
1998
Highly Cited
1998
The regulation of dietary cholesterol absorption was examined in C57BL/6 and transgenic mice with liver overexpression of the… Expand
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Highly Cited
1998
Highly Cited
1998
The specific effects of soybean protein on lipid metabolism were determined with highly purified soybean protein. At 5 wk of age… Expand
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