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chloroethylene oxide

Known as: 2-chloroethylene oxide, chlorooxirane 
National Institutes of Health

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2 relations

Broader (1)

Ethylene Oxide
analogs & derivatives

Papers overview

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2007
2007
Effect of substituents and conformations on the optical rotations of cyclic oxides and related compounds. relationship between the anomeric effect and optical rotation.
The effect of substituents on the specific rotation of substituted cyclic oxides (X = F, Cl, CN, and HCC) and related compounds… 
Highly Cited
2000
Highly Cited
2000
Synthesis of nucleosides and oligonucleotides containing adducts of acrolein and vinyl chloride.
Vinyl chloride and acrolein are important industrial chemicals. Both form DNA adducts, vinyl chloride after enzymatic oxidation… 
1999
1999
Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N(2),3-ethenoguanine.
Etheno adducts are formed after exposure to a number of carcinogens, including vinyl chloride, as well as endogenously as a… 
1998
1998
Detection of 1,N6-ethenoadenine in rat urine after chloroethylene oxide exposure.
The four etheno adducts of vinyl chloride formed in DNA, 1,N6-ethenoadenine (epsilonA), 3,N4-ethenocytosine, 1,N2-ethenoguanine… 
1986
1986
Mutagenic and promutagenic properties of DNA adducts formed by vinyl chloride metabolites.
Published results and work from this laboratory permit the characterization of the possible promutagenic lesions induced by… 
1986
1986
Reaction kinetics and cytosine adducts of chloroethylene oxide and chloroacetaldehyde: direct observation of intermediates by FTNMR and GC-MS.
As it is not yet known which are the important miscoding adducts formed in the reaction of the relatively unstable compound… 
1983
1983
Evidence of chloroethylene oxide being the reactive metabolite of vinyl chloride towards DNA: comparative studies with 2,2'-dichlorodiethylether.
The roles of chloroethylene oxide (CEO) and chloroacetaldehyde (CAA) in carcinogenicity of vinyl chloride (VC) have been studied… 
Highly Cited
1982
Highly Cited
1982
Labeled 1,N6-ethenoadenosine and 3,N4-ethenocytidine in hepatic RNA of mice given[ethyl-1,2(-3)H or ethyl-1(-14)C]ethyl carbamate (urethan).
Injection of a single dose of[ethyl-1,2(-3)H]or[ethyl-1(-14C]- ethyl carbamate into 12-day old male[C57BL/6 x C3H/He]F1 mice or… 
1981
1981
Modification of deoxyguanosine by chloroethylene oxide.
Reaction of deoxyguanosine in glacial acetic acid with chloroethylene oxide, a proposed reactive metabolite of vinyl chloride… 
Highly Cited
1980
Highly Cited
1980
Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in…
Repeated s.c. administration of chloroethylene oxide, a reactive metabolite of the carcinogen vinyl chloride, induced local… 
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