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chemokine receptor activity

Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

chemokine binding
chemokine receptor

Broader (1)

chemokine-mediated signaling pathway

Papers overview

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2017
2017
Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Chronic myelomonocytic leukemia (CMML) is a hematological malignancy characterized by uncontrolled proliferation of dysplastic… Expand
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2016
2016
Critical Analysis on the Mechanism of Action (MoA) of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma (MM)
Monoclonal antibodies (mAbs) targeting CD38 are demonstrating remarkable efficacy, particularly when combined with anti-MM agents… Expand
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Review
2011
Review
2011
Mechanisms regulating chemokine receptor activity
Co‐ordinated movement and controlled positioning of leucocytes is key to the development, maintenance and proper functioning of… Expand
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Review
2009
Review
2009
Chemokines and chemokine receptors as therapeutic targets in chronic kidney disease.
As other cytokine families, chemokines have multiple roles in local and systemic immune responses. In the kidney, the temporal… Expand
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Review
2008
Review
2008
Regulators of chemokine receptor activity as promising anticancer therapeutics.
Chemokines are a family of small proteins inducing directed cell migration via specific chemokine receptors, which play important… Expand
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Review
2008
Review
2008
Modulation of chemokine receptor activity through dimerization and crosstalk
Abstract.Chemokines are small, secreted proteins that bind to the chemokine receptor subfamily of class A G protein-coupled… Expand
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2005
2005
Biochemical and HIV-1 Coreceptor Properties of K26R, a New CCR5 Variant in China's Sichuan Population
Despite multiple exposures to HIV-1, some individuals remain uninfected. This resistance to HIV infection has been associated… Expand
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Review
2005
Review
2005
Soluble and cleaved forms of the urokinase-receptor: degradation products or active molecules?
The urokinase-mediated plasminogen activation (PA) system is involved in many physiological and pathological events that include… Expand
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2003
2003
Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity.
Cell membrane exposure to oxysterols, such as 22-hydroxycholesterol (22-OHC), has previously been shown to induce a suppressive… Expand
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Highly Cited
2001
Highly Cited
2001
Potent, Broad-Spectrum Inhibition of Human Immunodeficiency Virus Type 1 by the CCR5 Monoclonal Antibody PRO 140
ABSTRACT CCR5 serves as a requisite fusion coreceptor for clinically relevant strains of human immunodeficiency virus type 1 (HIV… Expand
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