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chemokine (C-X-C motif) ligand 12 signaling pathway

Known as: CXCL12 signaling pathway, SDF1 signaling pathway, stromal cell-derived factor-1 signaling pathway 
A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of… Expand
National Institutes of Health

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C-X-C motif chemokine 12 receptor activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Inhibition of CXCL12 Signaling Attenuates the Postischemic Immune Response and Improves Functional Recovery after Stroke
After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing… Expand
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Highly Cited
2011
Highly Cited
2011
Neutrophil Mobilization from the Bone Marrow during Polymicrobial Sepsis Is Dependent on CXCL12 Signaling
Neutrophils are essential for successful host eradication of bacterial pathogens and for survival to polymicrobial sepsis. During… Expand
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Highly Cited
2011
Highly Cited
2011
Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model
Increasing evidences indicate that CXCR4/CXCL12 signaling pathway plays a pivotal role in the process of distant site metastasis… Expand
2011
2011
CXCL12 rs1801157 polymorphism and expression in peripheral blood from breast cancer patients.
The role of chemokines has been extensively analyzed both in cancer risk and tumor progression. Among different cytokines, CXCR4… Expand
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Highly Cited
2010
Highly Cited
2010
Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis
Multiple sclerosis (MS) is a human demyelinating disease characterized by multifocal regions of inflammation, progressive myelin… Expand
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Highly Cited
2010
Highly Cited
2010
A pivotal role for CXCL12 signaling in HPV-mediated transformation of keratinocytes: clues to understanding HPV-pathogenesis in WHIM syndrome.
The WHIM syndrome, which features high susceptibility to human papillomavirus (HPV) infection, is a rare immunodeficiency… Expand
2005
2005
CXCL12 Signaling Is Independent of Jak2 and Jak3*
Janus kinases (Jaks) are a small family of cytoplasmic tyrosine kinases, critical for signaling by Type I and II cytokine… Expand
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2005
2005
Risk for HIV-1 Infection Associated With a Common CXCL12 (SDF1) Polymorphism and CXCR4 Variation in an African Population
CXC chemokine ligand 12 (CXCL12), or stromal cell-derived factor 1 (SDF1), is the only known natural ligand for the HIV-1… Expand
Review
2002
Review
2002
Comparison between granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the mobilization of peripheral blood stem cells
  • Y. Gazitt
  • Current opinion in hematology
  • 2002
    • Corpus ID: 5903436
Peripheral blood stem cells (PBSC) have become the preferred source of stem cells for autologous transplantation because of the… Expand
Review
2000
Review
2000
Distribution of three HIV-1 resistance-conferring polymorphisms (SDF1-3′A, CCR2-64I, and CCR5-Δ32) in global populations
Chemokine receptors (CCR5, CXCR4 and CCR2) have been shown to be important co-receptors for HIV infection. Mutations at CCR5… Expand
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