chemokine (C-X-C motif) ligand 12 signaling pathway
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After stroke, brain inflammation in the ischemic hemisphere hampers brain tissue reorganization and functional recovery. Housing… Expand Neutrophils are essential for successful host eradication of bacterial pathogens and for survival to polymicrobial sepsis. During… Expand Increasing evidences indicate that CXCR4/CXCL12 signaling pathway plays a pivotal role in the process of distant site metastasis… Expand The role of chemokines has been extensively analyzed both in cancer risk and tumor progression. Among different cytokines, CXCR4… Expand Multiple sclerosis (MS) is a human demyelinating disease characterized by multifocal regions of inflammation, progressive myelin… Expand The WHIM syndrome, which features high susceptibility to human papillomavirus (HPV) infection, is a rare immunodeficiency… Expand Janus kinases (Jaks) are a small family of cytoplasmic tyrosine kinases, critical for signaling by Type I and II cytokine… Expand CXC chemokine ligand 12 (CXCL12), or stromal cell-derived factor 1 (SDF1), is the only known natural ligand for the HIV-1… Expand Peripheral blood stem cells (PBSC) have become the preferred source of stem cells for autologous transplantation because of the… Expand Chemokine receptors (CCR5, CXCR4 and CCR2) have been shown to be important co-receptors for HIV infection. Mutations at CCR5… Expand