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chelerythrine

Known as: 1,2-dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Mitochondrial dysfunction is a prominent feature of most cardiovascular diseases. Angiotensin (Ang) II is an important stimulus… Expand
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Highly Cited
2004
Highly Cited
2004
Sanguinaria canadesis, Chelidonium majus and Macleya cordata have been used for centuries as alternative medicines. Currently the… Expand
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Highly Cited
2002
Highly Cited
2002
Background—Increased superoxide production contributes to reduced vascular nitric oxide (NO) bioactivity and endothelial… Expand
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Highly Cited
2002
Highly Cited
2002
Angiotensin II infusion causes endothelial dysfunction by increasing NAD(P)H oxidase-mediated vascular superoxide production… Expand
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Highly Cited
2001
Highly Cited
2001
Hyperglycemia is the major causal factor in the development of endothelial dysfunction in patients with diabetes mellitus… Expand
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Highly Cited
2000
Highly Cited
2000
The critical time for opening mitochondrial (mito) KATP channels, putative end effectors of ischemic preconditioning (PC), was… Expand
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Highly Cited
1996
Highly Cited
1996
Endothelium exposed to fluid shear stress (FSS) undergoes cell shape change, alignment and microfilament network remodeling in… Expand
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Highly Cited
1994
Highly Cited
1994
The present study investigated whether protein kinase C (PKC) plays a role in ischemic preconditioning in the rat heart… Expand
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Highly Cited
1994
Highly Cited
1994
The present studies were undertaken to characterize further the potential role of protein kinase C (PKC) in the regulation of… Expand
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Highly Cited
1990
Highly Cited
1990
The benzophenanthridine alkaloid chelerythrine is a potent, selective antagonist of the Ca++/phospholopid-dependent protein… Expand
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