chelerythrine

Known as: 1,2-dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The emerging literature implicates a role for glia/cytokines in persistent pain. However, the mechanisms by which these non… (More)
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Highly Cited
2007
Highly Cited
2007
Mitochondrial dysfunction is a prominent feature of most cardiovascular diseases. Angiotensin (Ang) II is an important stimulus… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Ischemic postconditioning protects the reperfused heart from infarction, and this protection is dependent on the… (More)
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Highly Cited
2003
Highly Cited
2003
The identification of small molecule inhibitors of antiapoptotic Bcl-2 family members has opened up new therapeutic opportunities… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Increased superoxide production contributes to reduced vascular nitric oxide (NO) bioactivity and endothelial… (More)
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Highly Cited
2001
Highly Cited
2001
Incubation of endothelial cells in vitro with high concentrations of glucose activates protein kinase C (PKC) and increases… (More)
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Highly Cited
2001
Highly Cited
2001
The role of protein kinase C (PKC) inhibition in cardiac myocyte apoptosis has not been well understood. We investigated the… (More)
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Highly Cited
2000
Highly Cited
2000
The critical time for opening mitochondrial (mito) K(ATP) channels, putative end effectors of ischemic preconditioning (PC), was… (More)
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Highly Cited
1994
Highly Cited
1994
The present study investigated whether protein kinase C (PKC) plays a role in ischemic preconditioning in the rat heart… (More)
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Highly Cited
1990
Highly Cited
1990
The benzophenanthridine alkaloid chelerythrine is a potent, selective antagonist of the Ca++/phospholopid-dependent protein… (More)
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