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chaetomellic acid A

Known as: 2-Butenedioic acid, 2-methyl-3-tetradecyl-, (Z)- 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
0119962017

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Related topics

1 relation

Broader (1)

Maleates

Related mentions per year

Related mentions per year

1975-2017
197019801990200020102020
chaetomellic acid A
Maleates

Papers overview

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2017
2017
The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction
Purpose. This study aimed to evaluate the effect of chronic treatment with chaetomellic acid A (CAA) on oxidative stress and… (More)
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2014
2014
Effect of Angiotensin II and Small GTPase Ras Signaling Pathway Inhibition on Early Renal Changes in a Murine Model of Obstructive Nephropathy
Tubulointerstitial fibrosis is a major feature of chronic kidney disease. Unilateral ureteral obstruction (UUO) in rodents leads… (More)
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2013
2013
Novel route to chaetomellic acid A and analogues: serendipitous discovery of a more competent FTase inhibitor.
A new practical route to chaetomellic acid A (ACA), based on the copper catalysed radical cyclization (RC) of (Z)-3-(2,2… (More)
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2006
2006
Inhibition of Ras/ERK1/2 signaling protects against postischemic renal injury.
The small GTPase p21 Ras and its downstream effectors play a central role in the control of cell survival and apoptosis. We… (More)
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2004
2004
Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b.
Three types of mono- and disaccharides 3a,b, 4a-c, 5, and some chaetomellic acid A analogs 6 and 42-44 were synthesized as… (More)
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2003
2003
Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase.
Rubber transferase, a cis-prenyltransferase, catalyzes the addition of thousands of isopentenyl diphosphate (IPP) molecules to an… (More)
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2002
2002
A facile synthesis of natural products chaetomellic acid A and 1,7(Z)- nonadecadiene-2,3-dicarboxylic acid.
Synthesis of recently isolated bioactive natural products chaetomellic acid A anhydride (1) and a novel 1,7(Z)-nonadecadiene-2,3… (More)
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2000
2000
Analysis of farnesyl transferase activity during hormone-induced maturation of Xenopus laevis oocytes.
Preincubation of Xenopus laevis oocytes with insulin or insulin-like growth factor 1 (IGF-1) resulted in inhibition of farnesyl… (More)
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1996
1996
Synthesis of Protein Farnesyltransferase and Protein Geranylgeranyltransferase Inhibitors: Rapid Access to Chaetomellic Acid A and Its Analogues.
A facile two-step stereospecific synthesis of the protein farnesyltransferase inhibitor chaetomellic acid A (1) and its analogues… (More)
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