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ceragenin CSA-13

Known as: CSA-13 ceragenin 
 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Steroids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance
Natural antimicrobial peptides and ceragenins, as non-peptide amphipathic mimics, have been proposed as anti-cancer agents. To… Expand
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2017
2017
Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo
BackgroundCationic antibacterial peptides (CAPs) and synthetic molecules mimicking the amphiphilic structure of CAPs, such as… Expand
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2016
2016
Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins
Core–shell magnetic nanoparticles (MNPs) are promising candidates in the development of new treatment methods against infections… Expand
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2015
2015
Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
The pleiotropic activity of human cathelicidin LL-37 peptide includes an ability to suppress development of colon cancer cells… Expand
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2013
2013
Ceragenin CSA-13 induces cell cycle arrest and antiproliferative effects in wild-type and p53 null mutant HCT116 colon cancer cells
Antimicrobial peptides of the cathelicidin family play a central role in the host defense system. Our group has reported… Expand
2012
2012
Molecular Dynamics and Experimental Investigations of Membrane Perturbation by Ceragenin CSA-13
Ceragenin CSA-13, a cholic acid derivative, has been reported as a novel template/ scaffold for development of more potent and… Expand
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2011
2011
Potential of ceragenin CSA‐13 and its mixture with pluronic F‐127 as treatment of topical bacterial infections
Aims:  Ceragenin CSA‐13 is a synthetic mimic of cationic antibacterial peptides, with facial amphiphilic morphology reproduced… Expand
2011
2011
In vitro Activities of the Novel Ceragenin CSA-13, Alone or in Combination with Colistin, Tobramycin, and Ciprofloxacin, against Pseudomonas aeruginosa Strains Isolated from Cystic Fibrosis Patients
Background: The rise in the rates of antibiotic resistance among Pseudomonas aeruginosa strains from cystic fibrosis (CF… Expand
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2009
2009
Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice
BackgroundThe worldwide appearance of drug-resistant strains of H. pylori motivates a search for new agents with therapeutic… Expand
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Highly Cited
2007
Highly Cited
2007
Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum.
OBJECTIVES The goal of this study was to evaluate the effects of DNA and F-actin [polyanions present in high concentration in… Expand
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