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ceragenin CSA-13

Known as: CSA-13 ceragenin 
National Institutes of Health

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1 relation

Broader (1)

Steroids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance
Natural antimicrobial peptides and ceragenins, as non-peptide amphipathic mimics, have been proposed as anti-cancer agents. To… 
2017
2017
Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo
Cationic antibacterial peptides (CAPs) and synthetic molecules mimicking the amphiphilic structure of CAPs, such as ceragenins… 
Highly Cited
2016
Highly Cited
2016
Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins
Core–shell magnetic nanoparticles (MNPs) are promising candidates in the development of new treatment methods against infections… 
2015
2015
Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
The pleiotropic activity of human cathelicidin LL-37 peptide includes an ability to suppress development of colon cancer cells… 
2013
2013
Ceragenin CSA-13 induces cell cycle arrest and antiproliferative effects in wild-type and p53 null mutant HCT116 colon cancer cells
Antimicrobial peptides of the cathelicidin family play a central role in the host defense system. Our group has reported… 
2012
2012
Molecular Dynamics and Experimental Investigations of Membrane Perturbation by Ceragenin CSA-13
Ceragenin CSA-13, a cholic acid derivative, has been reported as a novel template/ scaffold for development of more potent and… 
Highly Cited
2011
Highly Cited
2011
Potential of ceragenin CSA‐13 and its mixture with pluronic F‐127 as treatment of topical bacterial infections
Aims:  Ceragenin CSA‐13 is a synthetic mimic of cationic antibacterial peptides, with facial amphiphilic morphology reproduced… 
2011
2011
In vitro Activities of the Novel Ceragenin CSA-13, Alone or in Combination with Colistin, Tobramycin, and Ciprofloxacin, against Pseudomonas aeruginosa Strains Isolated from Cystic Fibrosis Patients
Background: The rise in the rates of antibiotic resistance among Pseudomonas aeruginosa strains from cystic fibrosis (CF… 
Highly Cited
2009
Highly Cited
2009
Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice
BackgroundThe worldwide appearance of drug-resistant strains of H. pylori motivates a search for new agents with therapeutic… 
Highly Cited
2007
Highly Cited
2007
Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum.
OBJECTIVES The goal of this study was to evaluate the effects of DNA and F-actin [polyanions present in high concentration in… 
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