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cephalosporinase activity

Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. [GOC:mlg]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2017
02419662017

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2000
2000
Carbapenem-resistant Pseudomonas aeruginosa with acquired bla(vim) metallo-beta-lactamase determinants, Italy.
To the Editor: Acquired metallo-ß-lactamase determinants in Pseudomonas aeruginosa and other major bacterial pathogens are of… (More)
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1997
1997
OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain.
Pseudomonas aeruginosa AH, isolated in Ankara, Turkey, was highly resistant to ceftazidime (MIC, 128 microg/ml) and produced a… (More)
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1994
1994
Insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides fragilis clinical isolates.
Bacteroides fragilis is an important opportunistic pathogen of humans and is resistant to many drugs commonly used to treat… (More)
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1994
1994
Three beta-lactamases isolated fromAeromonas salmonicida, including a carbapenemase not detectable by conventional methods
The β-lactamases of seven strains ofAeromonas salmonicida subsp.achromogenes resistant to amoxicillin (MIC>1024 mg/l) and… (More)
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1993
1993
Critical hydrogen bonding by serine 235 for cephalosporinase activity of TEM-1 beta-lactamase.
The role of Ser-235 in the catalytic mechanism of the TEM-1 beta-lactamase has been explored by the study of a mutant enzyme in… (More)
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1985
1985
Monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa.
Ten hybridomas which produced monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa were… (More)
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1985
1985
Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains ofEnterobacteriaceae
Sir, We report on the frequency of Enterobacteriaceae strains which produce plasmid-mediated beta-lactamases and specify the… (More)
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1980
1980
Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.
1. Mutants of Bacillus cereus 569/H/9 have been screened in a search for strains that synthesize variants of beta-lactamase II. 2… (More)
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1977
1977
Cefoxitin resistance to beta-lactamase: a major factor for susceptibility of bacteroides fragilis to the antibiotic.
Toluene-treated cell suspensions of Bacteroides fragilis were used to screen clinical isolates for the production of beta… (More)
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1973
1973
Cephalosporinase activity in Bacteroides fragilis.
Cephalosporinase activity was demonstrated in all of 10 strains of Bacteroides fragilis investigated. Low rates of hydrolysis of… (More)
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