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cephalosporinase activity

Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. [GOC:mlg]
National Institutes of Health

Papers overview

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2012
2012
Sulbactam and Clavulanic Acid: Studies of Enzyme Kinetics and Synergy with Ampicillin and Mezlocillin
The combination of i3-lactamase inhibitors with i3-lactamase-labile compounds (such as ampicillin or mezlocillin) provides a new… 
2004
2004
Detection and Characterization of β-Lactam Resistance in Bacillus cereus PTCC 1015
In the present study, detection, isolation, and characterization of β-lactamases from Bacillus cereus PTCC 1015 were investigated… 
2001
2001
TEM 1 / 3-Lactamase Structure Solved by Molecular Replacement and Refined Structure of the $ 235 A Mutant
  • 2001
  • Corpus ID: 49536455
/3-Lactamases are bacterial enzymes which catalyse the hydrolysis of the /%lactam ring of penicillins, cephalosporins and related… 
1987
1987
Concluding remarks
  • G. Gray
  • Philosophical Transactions of the Royal Society A…
  • 1987
  • Corpus ID: 43996891
Potential applications of synthetic seed technology to agriculture are numerous, but certain milestones are ahead. The driving… 
1987
1987
[Sulbactam and clavulanic acid: studies of enzyme kinetics and synergism with ampicillin and mezlocillin].
Both inhibitors clavulanic acid and sulbactam exhibit high affinity (Ki-values less than 10(-6) mol/l) to the beta-lactamases of… 
1985
1985
Monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa.
Ten hybridomas which produced monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa were… 
1985
1985
Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains ofEnterobacteriaceae
Sir, We report on the frequency of Enterobacteriaceae strains which produce plasmid-mediated beta-lactamases and specify the… 
1980
1980
Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.
1. Mutants of Bacillus cereus 569/H/9 have been screened in a search for strains that synthesize variants of beta-lactamase II. 2… 
1966
1966
Association of cephalosporinase activity, cephalothin resistance, and episome-mediated drug resistance in Klebsiella strains.
1965
1965
Cephalosporinase and penicillinase activity of Gram-negative bacteria.
SUMMARY: Sensitivity to ampicillin and cephalothin, the formation and induction of penicillinase and cephalosporinase, and the… 
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