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cephalosporinase activity

Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. [GOC:mlg]
National Institutes of Health

Papers overview

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2001
2001
TEM 1 / 3-Lactamase Structure Solved by Molecular Replacement and Refined Structure of the $ 235 A Mutant
  • 2001
  • Corpus ID: 49536455
/3-Lactamases are bacterial enzymes which catalyse the hydrolysis of the /%lactam ring of penicillins, cephalosporins and related… 
1987
1987
[Sulbactam and clavulanic acid: studies of enzyme kinetics and synergism with ampicillin and mezlocillin].
Both inhibitors clavulanic acid and sulbactam exhibit high affinity (Ki-values less than 10(-6) mol/l) to the beta-lactamases of… 
1985
1985
Monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa.
Ten hybridomas which produced monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa were… 
1980
1980
Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.
1. Mutants of Bacillus cereus 569/H/9 have been screened in a search for strains that synthesize variants of beta-lactamase II. 2… 
1966
1966
Association of cephalosporinase activity, cephalothin resistance, and episome-mediated drug resistance in Klebsiella strains.
1965
1965
Cephalosporinase and penicillinase activity of Gram-negative bacteria.
SUMMARY: Sensitivity to ampicillin and cephalothin, the formation and induction of penicillinase and cephalosporinase, and the…