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cephalosporinase activity

Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. [GOC:mlg]
National Institutes of Health

Papers overview

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2018
2018
Substitution of Alanine at Position 184 with Glutamic Acid in Escherichia coli PBP5 Ω-Like Loop Introduces a Moderate Cephalosporinase Activity
Escherichia coli PBP5, a DD-carboxypeptidase (DD-CPase), helps in maintaining cell shape and intrinsic β-lactam resistance… 
2005
2005
Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains ofEnterobacteriaceae
Sir, We report on the frequency of Enterobacteriaceae strains which produce plasmid-mediated beta-lactamases and specify the… 
1999
1999
Antibiotic susceptibilities of Yersinia enterocolitica and Y. intermedia isolates from aquatic environments.
Of 37 Yersinia isolates from various aquatic environments, seven were Y. enterocolitica and 30 Y. intermedia. These isolates were… 
Highly Cited
1997
Highly Cited
1997
OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain
Pseudomonas aeruginosa AH, isolated in Ankara, Turkey, was highly resistant to ceftazidime (MIC, 128 microg/ml) and produced a… 
1997
1997
Cephalosporin Substrate Specificity Determinants of TEM-1 β-Lactamase*
β-lactamase is a bacterial enzyme that catalyzes the hydrolysis of β-lactam antibiotics such as penicillins and cephalosporins… 
1985
1985
Monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa.
Ten hybridomas which produced monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa were… 
1980
1980
Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.
1. Mutants of Bacillus cereus 569/H/9 have been screened in a search for strains that synthesize variants of beta-lactamase II. 2… 
1976
1976
Induction of resistance in Staphylococcus aureus and Klebsiella pneumoniae by exposure to cephalothin and cefoxitin.
Six strains each of Staphylococcus aureus and Klebsiella pneumoniae were exposed to subinhibitory, but serially incremental… 
1966
1966
Association of cephalosporinase activity, cephalothin resistance, and episome-mediated drug resistance in Klebsiella strains.
1965
1965
Cephalosporinase and penicillinase activity of Gram-negative bacteria.
  • G. Ayliffe
  • Journal of general microbiology
  • 1965
  • Corpus ID: 35373412
SUMMARY: Sensitivity to ampicillin and cephalothin, the formation and induction of penicillinase and cephalosporinase, and the… 
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