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cephalosporinase activity

Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. [GOC:mlg]
National Institutes of Health

Papers overview

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2018
2018
Substitution of Alanine at Position 184 with Glutamic Acid in Escherichia coli PBP5 Ω-Like Loop Introduces a Moderate Cephalosporinase Activity
Escherichia coli PBP5, a DD-carboxypeptidase (DD-CPase), helps in maintaining cell shape and intrinsic β-lactam resistance… Expand
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2012
2012
Sulbactam and Clavulanic Acid: Studies of Enzyme Kinetics and Synergy with Ampicillin and Mezlocillin
The combination of i3-lactamase inhibitors with i3-lactamase-labile compounds (such as ampicillin or mezlocillin) provides a new… Expand
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2006
2006
Concluding remarks
On I am very pleased to have been given this opportunity to say a few words in closing this Royal Society scientific discussion… Expand
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2005
2005
Frequency of plasmid-determined beta-lactamases in 680 consecutively isolated strains ofEnterobacteriaceae
Sir, We report on the frequency of Enterobacteriaceae strains which produce plasmid-mediated beta-lactamases and specify the… Expand
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1999
1999
Antibiotic susceptibilities of Yersinia enterocolitica and Y. intermedia isolates from aquatic environments.
Of 37 Yersinia isolates from various aquatic environments, seven were Y. enterocolitica and 30 Y. intermedia. These isolates were… Expand
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1997
1997
OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain.
Pseudomonas aeruginosa AH, isolated in Ankara, Turkey, was highly resistant to ceftazidime (MIC, 128 microg/ml) and produced a… Expand
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1997
1997
Cephalosporin substrate specificity determinants of TEM-1 beta-lactamase.
beta-lactamase is a bacterial enzyme that catalyzes the hydrolysis of beta-lactam antibiotics such as penicillins and… Expand
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1985
1985
Monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa.
Ten hybridomas which produced monoclonal antibodies against species-specific cephalosporinase of Pseudomonas aeruginosa were… Expand
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1980
1980
Production of a variant of beta-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9.
1. Mutants of Bacillus cereus 569/H/9 have been screened in a search for strains that synthesize variants of beta-lactamase II. 2… Expand
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1966
1966
Association of cephalosporinase activity, cephalothin resistance, and episome-mediated drug resistance in Klebsiella strains.
 
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