cellular detoxification

Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
05101519772018

Papers overview

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2010
2010
The pregnane-X-receptor (PXR) is master gene overseeing detoxification of wide number of xenobiotics and is critical for… (More)
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2008
2008
Cells expressing elevated levels of allelic variants of human glutathione S-transferase P1 (GSTP1) and/or efflux transporters… (More)
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2008
2008
Mutated K-ras is frequently found in human malignancies and plays a key role in many signal transduction processes resulting in… (More)
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Highly Cited
2006
Highly Cited
2006
To what extent are the determinants of aging in animal species universal? Insulin/insulin-like growth factor (IGF)-1 signaling… (More)
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Highly Cited
2006
Highly Cited
2006
Temporal genomic profiling and whole-cell proteomic analyses were performed to characterize the dynamic molecular response of the… (More)
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Highly Cited
2005
Highly Cited
2005
Members of the ABC (for ATP binding cassette) superfamily of integral membrane transporters function in cellular detoxification… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Phase 1, phase 2, and cellular efflux transporters are critical components in intestinal barrier function… (More)
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2004
2004
ATP-binding cassette (ABC) transporters play important roles in drug efflux, but some may also function in cellular… (More)
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Highly Cited
2003
Highly Cited
2003
The nuclear factor-E2 p45-related factor (Nrf) 2 is a transcription factor for the antioxidant responsive element-mediated… (More)
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1990
1990
Toxic aldehydes, such as 4-hydroxy-2-nonenal (4HNE) and 2-nonenal (2NE), formed during lipid peroxidation have been isolated and… (More)
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