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cell fate determination

A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The mammalian mitochondrial electron transport chain (ETC) includes complexes I-IV, as well as the electron transporters… Expand
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Review
2018
Review
2018
Rapidly renewing tissues such as the intestinal epithelium critically depend on the activity of small-sized stem cell populations… Expand
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Highly Cited
2009
Highly Cited
2009
MicroRNAs have been implicated as having important roles in stem cell biology. MicroRNA-9 (miR-9) is expressed specifically in… Expand
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Highly Cited
2006
Highly Cited
2006
Oct4 and Nanog are transcription factors required to maintain the pluripotency and self-renewal of embryonic stem (ES) cells… Expand
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Highly Cited
2006
Highly Cited
2006
Hematopoietic stem cells and their progenitors exhibit multilineage patterns of gene expression. Molecular mechanisms underlying… Expand
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Highly Cited
2002
Highly Cited
2002
We have studied the role of Notch-1 and its antagonist Numb in the activation of satellite cells during postnatal myogenesis… Expand
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Highly Cited
2002
Highly Cited
2002
Stem cells—which have the capacity to self-renew and generate differentiated progeny—are thought to be maintained in a specific… Expand
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Highly Cited
2002
Highly Cited
2002
RBP-J is a key mediator of Notch signaling that regulates cell fate determination in various lineages. To investigate the… Expand
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Highly Cited
1996
Highly Cited
1996
In the vertebrate central nervous system, the retina has been a useful model for studies of cell fate determination. Recent… Expand
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Review
1995
Review
1995
A number of different intracellular signaling pathways have been shown to be activated by receptor tyrosine kinases. These… Expand
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