cell fate determination

A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
MicroRNAs have been implicated as having important roles in stem cell biology. MicroRNA-9 (miR-9) is expressed specifically in… (More)
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Review
2008
Review
2008
First identified as cell cycle inhibitors mediating the growth inhibitory cues of upstream signaling pathways, the cyclin-CDK… (More)
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Highly Cited
2006
Highly Cited
2006
Oct4 and Nanog are transcription factors required to maintain the pluripotency and self-renewal of embryonic stem (ES) cells… (More)
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Highly Cited
2006
Highly Cited
2006
Many stem cells (SCs) respond to Wnt signaling, but whether beta-catenin's DNA binding partners, the Tcfs, play a role in SCs in… (More)
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Highly Cited
2006
Highly Cited
2006
Hematopoietic stem cells and their progenitors exhibit multilineage patterns of gene expression. Molecular mechanisms underlying… (More)
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Highly Cited
2004
Highly Cited
2004
Flowers are icons in developmental studies of complex structures. The vast majority of 250,000 angiosperm plant species have… (More)
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Highly Cited
2002
Highly Cited
2002
We have studied the role of Notch-1 and its antagonist Numb in the activation of satellite cells during postnatal myogenesis… (More)
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Highly Cited
2002
Highly Cited
2002
Stem cells—which have the capacity to self-renew and generate differentiated progeny—are thought to be maintained in a specific… (More)
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Highly Cited
2002
Highly Cited
2002
RBP-J is a key mediator of Notch signaling that regulates cell fate determination in various lineages. To investigate the… (More)
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Highly Cited
1996
Highly Cited
1996
In the vertebrate central nervous system, the retina has been a useful model for studies of cell fate determination. Recent… (More)
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