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cell chemotaxis

The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0204019752017

Related topics

Related topics

2 relations

Broader (1)

cellular response to chemical stimulus

Narrower (1)

chemokine activity

Related mentions per year

Related mentions per year

1975-2018
197019801990200020102020
cell chemotaxis
chemokine activity
cellular response to chemical stimulus

Papers overview

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Highly Cited
2011
Highly Cited
2011
The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.
In lymphocytes, the phosphoinositide 3'-kinase (PI3K) isoform p110δ (PI3Kδ) transmits signals from surface receptors, including… (More)
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Highly Cited
2006
Highly Cited
2006
Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.
OBJECTIVE Reactive oxygen species (ROS) produced by NAD(P)H oxidases (Nox) play a significant role in the pathophysiology of… (More)
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Highly Cited
2003
Highly Cited
2003
Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells.
The diverse physiological functions of histamine are mediated through distinct histamine receptors. Mast cells are major… (More)
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Highly Cited
2003
Highly Cited
2003
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment
Leukotriene B4 (LTB4) was originally described as a potent lipid myeloid cell chemoattractant, rapidly generated from innate… (More)
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Highly Cited
2002
Highly Cited
2002
A cathelicidin family of human antibacterial peptide LL-37 induces mast cell chemotaxis.
The mast cell is one of the major effector cells in inflammatory reactions and can be found in most tissues throughout the body… (More)
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Highly Cited
2001
Highly Cited
2001
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis.
The role of the protein kinase Akt in cell migration is incompletely understood. Here we show that sphingosine-1-phosphate (S1P… (More)
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Highly Cited
2001
Highly Cited
2001
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells.
Sphingosine 1-phosphate (SPP) binds to members of the endothelial differentiation gene family (EDG) of receptors and leads to… (More)
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Highly Cited
2000
Highly Cited
2000
The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity.
We have previously shown that members of the ELR(+) CXC chemokine family, including IL-8; growth-related oncogenes alpha, beta… (More)
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Highly Cited
1999
Highly Cited
1999
Membrane raft microdomains mediate front-rear polarity in migrating cells.
The acquisition of spatial and functional asymmetry between the rear and the front of the cell is a necessary step for cell… (More)
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Highly Cited
1995
Highly Cited
1995
The functional role of the ELR motif in CXC chemokine-mediated angiogenesis.
In this study, we demonstrate that the CXC family of chemokines displays disparate angiogenic activity depending upon the… (More)
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