ceftobiprole

A broad-spectrum, fifth-generation, pyrrolidinone cephalosporin with antibacterial activity. Ceftobiprole binds to and inactivates penicillin-binding… (More)
National Institutes of Health

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2014
2014
The percentage of the dosing interval that the non-protein-bound plasma concentration is above the MIC (%fT>MIC) for… (More)
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Review
2009
Review
2009
Antibiotic resistance is a major public health concern, with fears expressed that we shortly will run out of antibiotics. In… (More)
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Highly Cited
2008
Highly Cited
2008
Ceftobiprole is the first broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA… (More)
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2008
2008
Methicillin-resistant Staphylococcus aureus (MRSA) is resistant to beta-lactam antibiotics because it expresses penicillin… (More)
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Review
2008
Review
2008
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection has become epidemic. Skin and soft-tissue… (More)
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Review
2007
Review
2007
Pseudomonas aeruginosa is a major cause of nosocomial infections. This organism shows a remarkable capacity to resist antibiotics… (More)
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Review
2006
Review
2006
Resistance to antimicrobials is a significant and growing problem, limiting treatment options, especially for serious Gram… (More)
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Review
2006
Review
2006
Methicillin-resistant Staphylococcus aureus (MRSA) strains cause serious nosocomial infections all over the world. Overall… (More)
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2005
2005
Ceftobiprole (previously known as BAL9141), an anti-methicillin-resistant Staphylococcus aureus cephalosporin, was very highly… (More)
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Highly Cited
2005
Highly Cited
2005
A total of 184 methicillin-resistant Staphylococcus aureus (MRSA) strains were collected from patients who sought treatment… (More)
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