cathepsin Z

Known as: Preprocathepsin P, EC 3.4.18.1, Cathepsin P 
A ubiquitously-expressed cysteine peptidase that exhibits carboxypeptidase activity. It is highly expressed in a variety of immune cell types and may… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The lysosomal cysteine proteases cathepsin B (Ctsb) and cathepsin Z (Ctsz, also called cathepsin X/P) have been implicated in… (More)
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Highly Cited
2008
Highly Cited
2008
Alpha-synuclein is likely to play a key role in the development of Parkinson's disease as well as other synucleinopathies. In… (More)
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Highly Cited
2006
Highly Cited
2006
The cysteine protease cathepsin S is highly expressed in malignant tissues. By using a mouse model of multistage murine… (More)
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Highly Cited
2004
Highly Cited
2004
We describe the successful use of RNA interference (RNAi) to investigate gene function in the human filarial parasite Onchocerca… (More)
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Highly Cited
2003
Highly Cited
2003
Human atherosclerotic lesions overexpress the lysosomal cysteine protease cathepsin S (Cat S), one of the most potent mammalian… (More)
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Highly Cited
2003
Highly Cited
2003
AbstractThere is increasing evidence that proteases other than caspases, for example, the lysosomal cathepsins B, D and L, are… (More)
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Highly Cited
2001
Highly Cited
2001
It has been suggested that lysosomes and the lysosomal proteases cathepsin D and B act as proapoptotic mediators of apoptosis, in… (More)
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Highly Cited
2001
Highly Cited
2001
Alteration of skeletal muscle protein breakdown is a hallmark of a set of pathologies, including sepsis, with negative… (More)
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Highly Cited
1996
Highly Cited
1996
A functional approach of gene cloning was applied to HeLa cells in an attempt to isolate positive mediators of programmed cell… (More)
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Highly Cited
1990
Highly Cited
1990
We investigated the possibility that cathepsin D, an estrogen-induced lysosomal protease, might have value as a prognostic factor… (More)
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