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cathepsin K
Known as:
Cathepsin K [Chemical/Ingredient]
, Cathepsin O
, Cathepsin X
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A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading…
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National Institutes of Health
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Related topics
Related topics
24 relations
Bone remodeling
CTSK gene
CTSO gene
CTSZ gene
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Broader (1)
caspase
Narrower (1)
procathepsin K
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
EFFECT OF ESTROGEN AND DIETARY LOADING ON RAT CONDYLAR CARTILAGE
Marko
2015
Corpus ID: 55625349
The temporomandibular joint (TMJ) is a synovial joint which attaches the mandible to the skull. The head of the mandibular…
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2015
2015
Correction: Expression Analysis of All Protease Genes Reveals Cathepsin K to Be Overexpressed in Glioblastoma
U. Verbovšek
,
H. Motaln
,
+4 authors
T. Lah
PLoS ONE
2015
Corpus ID: 54548337
There are errors in S6 and S7 Files. The original files could not be opened. Please view the correct files below.
2013
2013
Inhibition of cathepsin K: blocking osteoclast bone resorption and more
L. Duong
2013
Corpus ID: 72145401
Approved therapeutic agents that were developed for the treatment of osteoporosis, improve bone mass and reduce fracture…
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2013
2013
Photodynamic Therapy Using a Protease-Mediated Theranostic Agent Reduces Cathepsin-B Activity in Mouse Atheromata In Vivo
Soo-MinShon
,
YongdooChoi
,
+4 authors
Dong-EogKim
2013
Corpus ID: 92397876
Objective—To investigate whether an intravenously injected cathepsin-B activatable theranostic agent (L-SR15) would be cleaved in…
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2009
2009
Treatment with a Potent Cathepsin K Inhibitor Preserves Cortical and Trabecular Bone Mass in Ovariectomized Monkeys
G. Stroup
,
S. Sushanth Kumar
,
C. Jerome
Calcified Tissue International
2009
Corpus ID: 7429568
The cysteine protease cathepsin K is involved in osteoclast-mediated bone resorption. We evaluated the effect of daily oral…
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2006
2006
PKPD model for cathepsin K inhibition with K inhibition with balicatib and changes in bone turnover biomarkers, in particular and changes in bone turnover biomarkers, in particular NTx
N. Holford
,
Nitin Kaila
,
+4 authors
J. Steimer
2006
Corpus ID: 139001154
Background: Cathepsin K is a key enzyme for the breakdown of collagen during bone resorption. Balicatib inhibits cathepsin K. The…
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2001
2001
Inducible Binding of Bioactive Cathepsin C to the Cell Surface of Neutrophils
M. Campbell
,
S. Boukedes
,
E. Campbell
2001
Corpus ID: 51846759
Catalytically active cathepsin G that is bound to the cell surface of human neutrophils may play a variety of roles in normal…
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2001
2001
Pycnodysostosis with a Cathepsin K Mutation: A Case Report
Yamagiwa Hiroshi
,
Asaoka Mayumi
,
K. Hisayoshi
2001
Corpus ID: 55670636
Summary. Pycnodysostosis (PKND) is a type of osteosclerosing bone disease. Recent studies have demonstrated that several…
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1978
1978
Purification of bovine spleen collagenolytic cathepsin, (cathepsin N).
A. Ducastaing
,
D. Etherington
Biochemical Society Transactions
1978
Corpus ID: 10286777
Purification of Bovine Spleen Collagenolytic Cathepsin (Cathepsin N) ANDRE DUCASTAING* and DAVID J. ETHERINGTON Agricultural…
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Highly Cited
1977
Highly Cited
1977
The dissolution of insoluble bovine collagens by cathepsin B1, collagenolytic cathepsin and pepsin. The influence of collagen type, age and chemical purity on susceptibility.
D. Etherington
Connective Tissue Research
1977
Corpus ID: 40729196
Insoluble collagens were obtained from different bovine tissues using an exhaustive extraction procedure. Each collagen…
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