Skip to search formSkip to main contentSkip to account menu

cathepsin F

Known as: Cathepsin F [Chemical/Ingredient] 
A lysosomal papain-related cysteine proteinase that is expressed in a broad variety of cell types.
National Institutes of Health

Related topics

Related topics

8 relations
CTSF geneIn BloodProcess of secretionantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis.
Kufs disease, an adult-onset neuronal ceroid lipofuscinosis, is challenging to diagnose and genetically heterogeneous. Mutations… 
2012
2012
A cathepsin F-like peptidase involved in barley grain protein mobilization, HvPap-1, is modulated by its own propeptide and by cystatins
Among the C1A cysteine proteases, the plant cathepsin F-like group has been poorly studied. This paper describes the molecular… 
Highly Cited
2009
Highly Cited
2009
Cathepsin F Cysteine Protease of the Human Liver Fluke, Opisthorchis viverrini
Background The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between… 
Highly Cited
2006
Highly Cited
2006
Murine Cathepsin F Deficiency Causes Neuronal Lipofuscinosis and Late-Onset Neurological Disease
ABSTRACT Cathepsin F (cat F) is a widely expressed lysosomal cysteine protease whose in vivo role is unknown. To address this… 
Highly Cited
2004
Highly Cited
2004
Cysteine Protease Cathepsin F Is Expressed in Human Atherosclerotic Lesions, Is Secreted by Cultured Macrophages, and Modifies Low Density Lipoprotein Particles in Vitro*
During atherogenesis, low density lipoprotein (LDL) particles in the arterial intima become modified and fuse to form… 
Highly Cited
2000
Highly Cited
2000
Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages
The major histocompatibility complex (MHC) class II–associated invariant chain (Ii) regulates intracellular trafficking and… 
Highly Cited
1999
Highly Cited
1999
Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen.
A novel human cDNA encoding a cysteine protease of the papain family named cathepsin F is reported. The mature part of the… 
Highly Cited
1999
Highly Cited
1999
Molecular Cloning and Structural and Functional Characterization of Human Cathepsin F, a New Cysteine Proteinase of the Papain Family with a Long Propeptide Domain*
A cDNA encoding a new cysteine proteinase belonging to the papain family and called cathepsin F has been cloned from a human… 
1999
1999
The Human Cathepsin F Gene a Fusion Product between an Ancestral Cathepsin and Cystatin Gene
Abstract Human cathepsin F is a novel papain-like cysteine protease of unknown function. Here, we describe the complete human… 
Highly Cited
1998
Highly Cited
1998
Human Cathepsin F
A cDNA for a novel human papain-like cysteine protease, designated cathepsin F, has been cloned from a λgt10-skeletal muscle cDNA… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License