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Relapsing polychondritis (RP) is a systemic inflammatory disease primarily affecting not only the cartilaginous structures of the… Expand Adolescent idiopathic scoliosis (AIS) is widely recognized as a complex disorder with a strong genetic predisposition. In… Expand We have developed a mouse in which the Cre recombinase gene has been targeted to exon 1 of the matrilin-1 gene (Matn1) to… Expand The extracellular matrix of the intervertebral disc structures contains many molecules also found in cartilage. The extremely… Expand BackgroundIn a previous study, a number of genes, associated with spine musculoskeletal deformity phenotypes in mouse and in… Expand The cartilage oligomeric matrix protein (COMP) and matrilins are abundant non-collagenous proteins in the cartilage extracellular… Expand Native supramolecular assemblies containing collagen VI microfibrils and associated extracellular matrix proteins were isolated… Expand Matrilin-3 is a recently identified member of the superfamily of proteins containing von Willebrand factor A-like domains and is… Expand The matrilin family at present has four members that all share a structure made up of von Willebrand factor A domains, epidermal… Expand A mouse cDNA encoding a novel member of the von Willebrand factor type A-like module superfamily was cloned. The protein… Expand