carboxytolbutamide

Known as: 1-butyl-3-(4-carboxyphenyl)sulfonylurea, 4-(((butylamino)carbonyl)amino)sulfonylbenzoic acid, tolbutamide carboxylic acid 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1960-2013
012319602013

Papers overview

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2004
2004
The hypoglycaemic drug tolbutamide is used for assessment of CYP2C9 activity in vivo. However, therapeutically active doses of… (More)
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2003
2003
The metabolic activity of CYP2C9 in 16 subjects expressing four different genotypes (CYP2C9*1/*1, *1/*2, *1/*3, and *2/*2) was… (More)
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2003
2003
AIM Our goal was to investigate whether artemisinin autoinduction is caused by an increase in cytochrome P450 (CYP) 2B6 or CYP2C9… (More)
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2002
2002
OBJECTIVES Multiple single-nucleotide polymorphisms in the gene encoding cytochrome P450 (CYP) 2C9 have been identified, but the… (More)
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2001
2001
OBJECTIVE Our objective was to examine the interaction between fluvoxamine and tolbutamide to confirm that fluvoxamine inhibits… (More)
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1990
1990
The present study has validated kinetically a convenient method to measure tolbutamide hydroxylation capacity in human beings by… (More)
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1988
1988
Specific, high affinity sulfonylurea receptors were characterized on membranes of an insulin-secreting hamster beta cell line… (More)
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1987
1987
The mechanisms by which glyburide and tolbutamide signal insulin secretion were examined using a beta cell line (Hamster insulin… (More)
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1986
1986
This study was designed to compare the effects of equivalent therapeutic doses of two H2 antagonists, cimetidine and ranitidine… (More)
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1981
1981
A high-performance liquid chromatographic method was developed for the simultaneous measurement of tolbutamide and its major… (More)
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